克罗登斯E-J，一种从肾茶地上部分提取的具有抗菌活性的咖啡酸衍生物。
Clerodens E-J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus.
作者信息
Li Qing, He Ying-Na, Shi Xiao-Wei, Kang Li-Ying, Niu Li-Ying, Wang Xin-Guo, Feng Wei
机构信息
Hebei TCM Formula Granule Engineering & Technology Research Center, Hebei University of Chinese Medicine, Shijiazhuang 050091, China.
School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang 050017, China.
出版信息
Fitoterapia. 2016 Oct;114:110-114. doi: 10.1016/j.fitote.2016.08.021. Epub 2016 Sep 1.
Six new caffeic acid derivatives, Clerodens E-J (1-6) were isolated from the aerial part of Clerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant strains of bacteria in vitro.
从肾茶地上部分分离得到6个新的咖啡酸衍生物，肾茶E-J（1-6）。通过广泛的光谱分析，包括核磁共振（NMR）、质谱（MS）和电子圆二色谱（ECD）数据对其结构进行了阐明。化合物1在体外对耐药菌株显示出中等抗菌活性。
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