Bioinformatics, University of Arkansas Little Rock, 2804 S. University, Little Rock, 72204, AR, USA.
Computer Science, University of Central Arkansas, 201 Donaghey Avenue, Conway, 72035, AR, USA.
BMC Bioinformatics. 2019 Mar 14;20(Suppl 2):91. doi: 10.1186/s12859-019-2625-8.
Dermoscopy is one of the common and effective imaging techniques in diagnosis of skin cancer, especially for pigmented lesions. Accurate skin lesion border detection is the key to extract important dermoscopic features of the skin lesion. In current clinical settings, border delineation is performed manually by dermatologists. Operator based assessments lead to intra- and inter-observer variations due to its subjective nature. Moreover it is a tedious process. Because of aforementioned hurdles, the automation of lesion boundary detection in dermoscopic images is necessary. In this study, we address this problem by developing a novel skin lesion border detection method with a robust edge indicator function, which is based on a meshless method.
Our results are compared with the other image segmentation methods. Our skin lesion border detection algorithm outperforms other state-of-the-art methods. Based on dermatologist drawn ground truth skin lesion borders, the results indicate that our method generates reasonable boundaries than other prominent methods having Dice score of 0.886 ±0.094 and Jaccard score of 0.807 ±0.133.
We prove that smoothed particle hydrodynamic (SPH) kernels can be used as edge features in active contours segmentation and probability map can be employed to avoid the evolving contour from leaking into the object of interest.
皮肤镜检查是诊断皮肤癌的常用且有效的成像技术之一,尤其是对色素性病变。准确的皮肤病变边界检测是提取皮肤病变重要皮肤镜特征的关键。在当前的临床环境中,边界描绘是由皮肤科医生手动完成的。由于其主观性,基于操作员的评估会导致观察者内和观察者间的差异。此外,这是一个繁琐的过程。由于上述障碍,皮肤镜图像中病变边界的自动检测是必要的。在这项研究中,我们通过开发一种新的基于无网格方法的稳健边缘指示函数的皮肤病变边界检测方法来解决这个问题。
我们将结果与其他图像分割方法进行了比较。我们的皮肤病变边界检测算法优于其他最先进的方法。基于皮肤科医生绘制的皮肤病变边界的真实情况,结果表明,与其他著名方法相比,我们的方法产生了更合理的边界,其 Dice 得分为 0.886 ±0.094,Jaccard 得分为 0.807 ±0.133。
我们证明了平滑粒子流体动力学(SPH)核可以用作主动轮廓分割中的边缘特征,并且可以使用概率图来避免演化轮廓泄漏到感兴趣的对象中。