Inserm U1148, LVTS, Université Paris 13, Sorbonne Paris Cité, Bobigny, France.
Chem Commun (Camb). 2019 Apr 2;55(28):4055-4058. doi: 10.1039/c8cc09476d.
Gold nanoraspberries were synthesized by a seed-mediated synthesis with polyethylene glycol-functionalized bisphosphonates. The original structure shifted the optical absorption to infrared, revealing very efficient photothermal properties within the 2nd biological transparency window and leading to cancer cell necrosis at moderate intracellular doses and low (safe) laser power.
金纳米刺梨果通过种子介导的合成方法，用聚乙二醇功能化双膦酸盐合成。原始结构将光吸收转移到红外区，在第二个生物透明窗口内显示出非常有效的光热性能，导致中等细胞内剂量和低（安全）激光功率下的癌细胞坏死。
