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用于汗液中葡萄糖检测的聚对苯二甲酸乙二醇酯 (PET) 薄膜电化学传感器。

A thin film polyethylene terephthalate (PET) electrochemical sensor for detection of glucose in sweat.

机构信息

Department of Chemistry, Zhejiang University, Hangzhou 310058, China.

Department of Chemistry, Zhejiang University, Hangzhou 310058, China.

出版信息

Talanta. 2019 Jun 1;198:86-92. doi: 10.1016/j.talanta.2019.01.104. Epub 2019 Jan 30.

Abstract

In this work, a thin film PET based gold electrode (PGE) glucose sensor was fabricated through ultraviolet mediated chemical plating technique. Compared with the most existing wearable thin film gold electrode sensors, the PGE-glucose sensor is simple, low cost and minimum instrumentation was required. The proposed glucose sensor revealed a sensitivity of 22.05 μA mM cm in a linear range from 0.02 to 1.11 mM with a low detection limit of 2.7 μM (S/N = 3). The PGE-glucose sensor had a good selectivity and was not interfered by lactic acid, urea, acetaminophen, uric acid, dopamine and ascorbic acid. Additionally, it exhibited good reproducibility and long-term stability over four weeks. Finally, the disposable PGE-glucose sensor was successfully applied to determine the glucose in sweat and commercial beverage accurately.

摘要

本工作采用紫外光介导化学镀技术制备了一种基于聚对苯二甲酸乙二醇酯(PET)的薄膜金电极(PGE)葡萄糖传感器。与大多数现有的可穿戴薄膜金电极传感器相比,PGE-葡萄糖传感器简单、低成本,所需仪器最少。所提出的葡萄糖传感器在 0.02 至 1.11 mM 的线性范围内具有 22.05 μA mM cm 的灵敏度,检测限低至 2.7 μM(S/N=3)。PGE-葡萄糖传感器具有良好的选择性,不受乳酸、尿素、对乙酰氨基酚、尿酸、多巴胺和抗坏血酸的干扰。此外,它在四周内表现出良好的重现性和长期稳定性。最后,一次性 PGE-葡萄糖传感器成功地应用于准确测定汗液和商业饮料中的葡萄糖。

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