Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Arch Gerontol Geriatr. 2019 May-Jun;82:251-258. doi: 10.1016/j.archger.2019.03.003. Epub 2019 Mar 6.
To study the association between country of birth and incident dementia in several immigrant groups in Sweden.
The study population included all adults (n = 3,286,624) aged 45 years and older in Sweden. Dementia was defined as having at least one registered diagnosis of dementia in the National Patient Register. The incidence of dementia in different immigrant groups, using Swedish-born as referents, was assessed by Cox regression, expressed in hazard ratios (HRs) and 95% confidence intervals (CI). All models were stratified by sex and adjusted for age, geographical residence in Sweden, educational level, marital status, and neighbourhood socioeconomic status.
A total of 136,713 individuals had a registered dementia event, i.e. 4.2%; 3.6% among men and 4.9% among women. After adjusting for confounders, in general, there was a lower incidence of dementia among both male immigrants (HR 0.85, 0.83-0.88) and female immigrants (HR 0.93, 0.91-0.95) compared to their Swedish-born counterparts. Among immigrant groups, a higher incidence (HR, 95%CI) of dementia was observed among men from Finland (1.14, 1.08-1.20), Bosnia (1.61, 1.18-2.20), Estonia (1.25, 1.10-1.43) and Russia (1.37, 1.12-1.69), and women from Finland (1.20 1.15-1.24) and Norway (1.14, 1.07-1.22).
Risk of dementia was lower in immigrants in general compared to the Swedish-born population; however there were substantial differences among immigrant groups in risk of dementia. Developing dementia in a new country with a different language could cause problems for both patients and the health care staff.
研究在瑞典的几个移民群体中,出生国与痴呆发病之间的关系。
研究人群包括瑞典所有年龄在 45 岁及以上的成年人(n=3,286,624)。痴呆的定义是国家患者登记处至少有一次痴呆的登记诊断。使用瑞典出生者作为参照,通过 Cox 回归评估不同移民群体的痴呆发病率,以风险比(HR)和 95%置信区间(CI)表示。所有模型均按性别分层,并根据年龄、在瑞典的地理居住地点、教育程度、婚姻状况和邻里社会经济地位进行调整。
共有 136,713 人发生了登记的痴呆事件,即 4.2%;男性为 3.6%,女性为 4.9%。在调整了混杂因素后,一般来说,男性移民(HR 0.85,0.83-0.88)和女性移民(HR 0.93,0.91-0.95)的痴呆发病率均较低。在移民群体中,芬兰(1.14,1.08-1.20)、波斯尼亚(1.61,1.18-2.20)、爱沙尼亚(1.25,1.10-1.43)和俄罗斯(1.37,1.12-1.69)男性移民以及芬兰(1.20,1.15-1.24)和挪威(1.14,1.07-1.22)女性移民的痴呆发病率较高(HR,95%CI)。
与瑞典出生的人群相比,移民的痴呆风险总体较低;然而,移民群体之间的痴呆风险存在很大差异。在一个语言不同的新国家患上痴呆症可能会给患者和医护人员带来问题。