Indiana University School of Nursing, 600 Barnhill Drive, Indianapolis, IN 46202, United States.
University of Kentucky College of Nursing, 2201 Regency Road, Suite 403, Lexington, KY 40503, United States.
Heart Lung. 2019 May-Jun;48(3):201-207. doi: 10.1016/j.hrtlng.2019.02.002. Epub 2019 Mar 14.
Patients with advanced heart failure (HF) experience many burdensome symptoms that increase patient suffering.
Comparative secondary analysis of 347 patients with advanced HF. Symptom burden was measured with the Memorial Symptom Assessment Scale-HF. Depression was measured using the Patient Health Questionnaire-9.
Mean number of symptoms was 13.6. The three most frequent symptoms were non-cardiac pain, shortness of breath, and lack of energy. Patients with depression reported higher symptom burden. Symptom burden differed when compared by gender. Women reported higher symptom burden for other pain, dry mouth, swelling of the arms and legs, sweats, feeling nervous, nausea, and vomiting. Men reported higher symptom burden with sexual problems.
Given the high rates of symptoms and distress, interventions are needed to alleviate the symptom burden of patients with advanced HF. Reported symptom burden in patients with advanced heart failure was higher when depressive symptoms were present. Women reported varied number and severity of symptoms than men.
患有晚期心力衰竭（HF）的患者会经历许多使患者痛苦增加的负担性症状。
对 347 例晚期 HF 患者进行比较性二次分析。使用 Memorial Symptom Assessment Scale-HF 测量症状负担。使用 Patient Health Questionnaire-9 测量抑郁。
平均症状数为 13.6。最常见的三种症状是非心脏疼痛、呼吸急促和乏力。患有抑郁症的患者报告的症状负担更高。按性别比较时，症状负担存在差异。女性报告的其他疼痛、口干、手臂和腿部肿胀、出汗、紧张、恶心和呕吐的症状负担更高。男性报告性问题的症状负担更高。
鉴于症状和痛苦的发生率较高，需要采取干预措施来减轻晚期 HF 患者的症状负担。存在抑郁症状时，报告的晚期心力衰竭患者的症状负担更高。女性报告的症状数量和严重程度比男性更多样化。
