Klepstad Pia Katrin, Nordseth Trond, Sikora Normunds, Klepstad Pål
Faculty of Medicine, Riga Stradins University, Riga, Latvia.
Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway,
Ther Clin Risk Manag. 2019 Feb 25;15:315-322. doi: 10.2147/TCRM.S192630. eCollection 2019.
Patients transferred from an intensive care unit (ICU) to a general ward are at risk for clinical deterioration. The aim of the study was to determine if an increase in National Early Warning Score (NEWS) value predicted worse outcomes in surgical ward patients previously treated in the ICU.
A retrospective observational study was conducted in a cohort of gastrointestinal surgery patients after transfer from an ICU/high dependency unit (HDU). NEWS values were collected throughout the ward admission. Clinical deterioration was defined by ICU readmission or death. The ability of NEWS to predict clinical deterioration was determined using a linear mixed effect model.
We included 124 patients, age 65.9±14.5, 60% males with an ICU Simplified Acute Physiology Score II 33.8±12.7. No patients died unexpectedly at the ward and 20 were readmitted to an ICU/HDU. The NEWS values increased by a mean of 0.15 points per hour (intercept 3.7, <0.001) before ICU/HDU readmission according to the linear mixed effect model. NEWS at transfer from ICU was the only factor that predicted readmission (OR 1.32; 95% CI 1.01-1.72; =0.04) at the time of admission to the ward.
Clinical deterioration of surgical patients was preceded by an increase in NEWS.
从重症监护病房(ICU)转入普通病房的患者存在临床病情恶化的风险。本研究的目的是确定国民早期预警评分(NEWS)值的升高是否预示着先前在ICU接受治疗的外科病房患者会有更差的预后。
对一组从ICU/高依赖病房(HDU)转出的胃肠外科患者进行了一项回顾性观察研究。在整个病房住院期间收集NEWS值。临床病情恶化定义为再次入住ICU或死亡。使用线性混合效应模型确定NEWS预测临床病情恶化的能力。
我们纳入了124例患者,年龄65.9±14.5岁,60%为男性,ICU简化急性生理学评分II为33.8±12.7。在病房中没有患者意外死亡,20例患者再次入住ICU/HDU。根据线性混合效应模型,在再次入住ICU/HDU之前,NEWS值平均每小时增加0.15分(截距3.7,<0.001)。从ICU转出时的NEWS是预测病房入院时再次入住的唯一因素(比值比1.32;95%置信区间1.01 - 1.72;P = 0.04)。
外科患者的临床病情恶化之前NEWS会升高。