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石榴的摄入会影响体重和身体成分吗?一项随机对照临床试验的系统评价和荟萃分析。

Does pomegranate consumption affect weight and body composition? A systematic review and meta-analysis of randomized controlled clinical trials.

机构信息

Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Phytother Res. 2019 May;33(5):1277-1288. doi: 10.1002/ptr.6322. Epub 2019 Mar 18.

DOI:10.1002/ptr.6322
PMID:30882964
Abstract

Pomegranate is rich in tannins, polyphenols, flavonoids, and several other types of antioxidant compounds whose role in weight loss has been shown in previous studies. However, the results have been mixed regarding the effects of pomegranate consumption on weight loss. Electronic databases such as PubMed, Scopus, ISI Web of Science, and Google Scholar were systematically searched up to May 2018 for controlled clinical trials assessing the effect of pomegranate consumption on weight loss. A random effects model was used to calculate the weighted mean difference (WMD) and 95% confidence interval (CI) as the difference between the mean for the intervention and control groups. Thirteen randomized controlled trials (including 513 participants) were included in the present meta-analysis. Compared with the control groups, there was no significant reduction in bodyweight, body mass index, waist circumference, and body fat percentage after pomegranate consumption (WMD = -0.23 kg, 95% CI: -0.94, 0.47, P = 0.515; WMD = -0.12 kg/m , 95% CI: -0.29, 0.03, P = 0.132; WMD = -0.08 cm, 95% CI: -0.33, 0.17, P = 0.534; WMD = -0.05, 95% CI: -1.66, 1.55, P = 0.947, respectively). According to the results of the present systematic review and meta-analysis, there was no significant effect of pomegranate consumption on weight and body composition indices.

摘要

石榴富含单宁、多酚、类黄酮和其他几种抗氧化化合物,先前的研究已经证明它们在减肥中的作用。然而,关于石榴消费对减肥的影响,结果一直存在差异。截至 2018 年 5 月,我们系统地检索了 PubMed、Scopus、ISI Web of Science 和 Google Scholar 等电子数据库,以评估评估石榴消费对体重减轻影响的对照临床试验。使用随机效应模型计算加权均数差(WMD)和 95%置信区间(CI)作为干预组和对照组之间的平均值差异。本荟萃分析共纳入 13 项随机对照试验(包括 513 名参与者)。与对照组相比,石榴消费后体重、体重指数、腰围和体脂百分比没有显著降低(WMD=-0.23kg,95%CI:-0.94,0.47,P=0.515;WMD=-0.12kg/m,95%CI:-0.29,0.03,P=0.132;WMD=-0.08cm,95%CI:-0.33,0.17,P=0.534;WMD=-0.05,95%CI:-1.66,1.55,P=0.947)。根据本系统评价和荟萃分析的结果,石榴消费对体重和身体成分指标没有显著影响。

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