Brosel Sonja, Strupp Michael
Department Biology II, Division of Neurobiology, Ludwig-Maximilians-University Munich, Munich, Germany.
Department of Neurology and German Center for Vertigo and Balance Disorders, Ludwig Maximilians University, Munich, Munich, Germany.
Subcell Biochem. 2019;91:195-225. doi: 10.1007/978-981-13-3681-2_8.
The world's population is ageing due to increased hygiene and improved medical care. Dizziness and imbalance frequently affect the elderly and is most common among individuals over the age of 60. In this age group approximately 30% of the population experience these debilitating symptoms at some point. They contribute to falls and frailty, which often result in hospitalization causing tremendous cost for the health care systems, and increased mortality. To make the matters worse balance disorders are often complex. Physicians face the difficulty of diagnosing the patient with the exact disorder especially since each disorder may manifest differently in each patient. In addition, several treatment options exist, however, with a low level of evidence. This chapter summarizes the underlying degenerative processes of the peripheral as well as the central vestibular system, diagnostic tools, the most common balance disorders in the elderly, and possible treatment options of these disorders.
由于卫生条件的改善和医疗保健的进步,世界人口正在老龄化。头晕和平衡失调经常影响老年人,在60岁以上的人群中最为常见。在这个年龄组中,约30%的人在某些时候会经历这些使人衰弱的症状。它们会导致跌倒和身体虚弱,常常导致住院,给医疗保健系统带来巨大成本,并增加死亡率。更糟糕的是,平衡失调往往很复杂。医生面临着准确诊断患者具体病症的困难,尤其是因为每种病症在每个患者身上的表现可能不同。此外,虽然有几种治疗选择,但证据水平较低。本章总结了外周以及中枢前庭系统潜在的退行性过程、诊断工具、老年人最常见的平衡失调以及这些失调可能的治疗选择。