Machii T, Kimura H, Ueda E, Chujo T, Morita T, Katagiri S, Tagawa S, Kitani T
Acta Haematol. 1986;75(1):26-9. doi: 10.1159/000206075.
Distribution of membrane-bound Gc protein (mGc) in normal lymphocyte subpopulations and leukemic lymphocytes was studied using a rabbit antiserum specific to Gc protein. Forty to fifty percent of the normal peripheral blood mononuclear cells were stained with anti-Gc antiserum by membrane immunofluorescence, and almost all of the B cells (B1+) and NK cells (Leu 11+) were mGc-positive. Only a few resting T cells (T3+) reacted with anti-Gc, but mGc appeared in a significant number of the T cells after activation by PHA. The distribution of mGc on leukemic lymphocytes of various types nearly corresponded to that in normal lymphocyte subpopulations.
使用针对Gc蛋白的兔抗血清研究了膜结合Gc蛋白（mGc）在正常淋巴细胞亚群和白血病淋巴细胞中的分布。40%至50%的正常外周血单个核细胞通过膜免疫荧光法被抗Gc抗血清染色，几乎所有B细胞（B1+）和NK细胞（Leu 11+）均为mGc阳性。仅有少数静止T细胞（T3+）与抗Gc反应，但经PHA激活后，大量T细胞出现mGc。各类白血病淋巴细胞上mGc的分布与正常淋巴细胞亚群中的分布几乎一致。
