Abdel-Salam E, Peters P A, Abdel Meguid A E, Abdel Meguid A A, Mahmoud A A
Am J Trop Med Hyg. 1986 Jul;35(4):786-90. doi: 10.4269/ajtmh.1986.35.786.
A large scale mollusciciding and chemotherapy program in the Fayoum area of Egypt was reported to have decreased prevalence of schistosomiasis haematobia from 46% to 7% in approximately 12 years. In order to assess the uniformity of results reported, we have studied the prevalence and intensity of urinary tract disease in a random sample of children aged 6 months-12 years in 3 areas selected on the basis of distance from the main canal supplying Fayoum and where mollusciciding was applied. Only 1 location near the main canal showed low prevalence (2.2%), while in the other 2 areas prevalence was 75.3% and 61.3%. Intensity of infection and disease were significantly more in the latter 2 locations. Following chemotherapy, a marked reduction in prevalence and intensity of infection and reversal of pathology was seen. Since the reported favorable results of the Fayoum project were used to implement a wider control program in southern Egypt, an independent assessment must be included in future plans.
据报道,埃及法尤姆地区一项大规模的灭螺和化疗计划在大约12年的时间里将埃及血吸虫病的患病率从46%降至7%。为了评估所报告结果的一致性,我们研究了在根据距供应法尤姆的主要运河的距离选择的3个地区中,6个月至12岁儿童随机样本中的泌尿系统疾病患病率和感染强度。只有靠近主要运河的1个地点患病率较低(2.2%),而其他2个地区的患病率分别为75.3%和61.3%。后2个地点的感染和疾病强度明显更高。化疗后,患病率和感染强度显著降低,病理状况得到逆转。由于法尤姆项目所报告的良好结果被用于在埃及南部实施更广泛的控制计划,因此未来的计划必须纳入独立评估。