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A TNF-NF-κB-STAT3 loop triggers resistance of glioma-stem-like cells to Smac mimetics while sensitizing to EZH2 inhibitors.

作者信息

Tannous Bakhos A, Badr Christian E

机构信息

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

Neuroscience Program, Harvard Medical School, Boston, MA, USA.

出版信息

Cell Death Dis. 2019 Mar 19;10(4):268. doi: 10.1038/s41419-019-1505-5.

DOI:10.1038/s41419-019-1505-5
PMID:30890700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6425042/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4796/6425042/799af5cf4a19/41419_2019_1505_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4796/6425042/799af5cf4a19/41419_2019_1505_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4796/6425042/799af5cf4a19/41419_2019_1505_Fig1_HTML.jpg

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Cell Death Discov. 2019 Mar 4;5:72. doi: 10.1038/s41420-019-0155-9. eCollection 2019.
2
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J Hematol Oncol. 2018 Jan 15;11(1):9. doi: 10.1186/s13045-017-0547-3.
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Front Oncol. 2022 Aug 10;12:965638. doi: 10.3389/fonc.2022.965638. eCollection 2022.
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Adv Drug Deliv Rev. 2022 Feb;181:114082. doi: 10.1016/j.addr.2021.114082. Epub 2021 Dec 16.
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