Yuan Hongmei, Lei Huilan, Gu Peng, Ma Lang, Qiu Li
Department of Medical Ultrasound, Laboratory of Ultrasound Imaging Drug, West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China.
Department of Ultrasound, Sichuan Key Laboratory of Medical Imaging, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, People's Republic of China.
Int J Gen Med. 2021 Jan 12;14:51-55. doi: 10.2147/IJGM.S287405. eCollection 2021.
Multiple myeloma (MM) in the breast has been rarely documented. However, there are no reports on concurrent masses of chest wall soft tissue and breast as the primary symptoms for MM. Herein, we report a case of a 68-year-old woman presented with masses in her right breast and chest wall for 1 month. She recalled having xerophthalmia and xerostomia for 2 years without taking any test to search for the cause of these symptoms. Ultrasonography (US) and computed tomography (CT) examination revealed masses in the right breast and chest wall. Both lesions of the breast and chest wall were confirmed to be plasma cell tumors by ultrasound-guided puncture biopsy and MM was confirmed by bone marrow examination. Meanwhile, Sjogren's syndrome (SS) was diagnosed by the positive expression of antibodies against antinuclear, Ro/SSA and La/SSB. After three courses of chemotherapy for MM, the symptoms of SS were significantly alleviated and the masses in the chest wall and breast disappeared.
乳腺多发性骨髓瘤（MM）鲜有文献记载。然而，尚无关于以胸壁软组织和乳腺同时出现肿块为MM主要症状的报道。在此，我们报告一例68岁女性，其右侧乳腺和胸壁出现肿块1个月。她回忆有2年的干眼症和口干症，但未进行任何检查以寻找这些症状的病因。超声（US）和计算机断层扫描（CT）检查显示右侧乳腺和胸壁有肿块。经超声引导穿刺活检，乳腺和胸壁的病变均被确诊为浆细胞瘤，骨髓检查确诊为MM。同时，通过抗核抗体、Ro/SSA和La/SSB抗体的阳性表达诊断为干燥综合征（SS）。经过三个疗程的MM化疗后，SS症状明显缓解，胸壁和乳腺的肿块消失。
