• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

输注含中链甘油三酯的乳剂用于肠外营养的代谢后果:与传统脂质的比较研究

The metabolic consequences of infusing emulsions containing medium chain triglycerides for parenteral nutrition: a comparative study with conventional lipid.

作者信息

Dennison A R, Ball M, Crowe P J, White K, Hands L, Watkins R M, Kettlewell M

出版信息

Ann R Coll Surg Engl. 1986 May;68(3):119-21.

PMID:3089123
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2498123/
Abstract

In order to test the hypothesis that medium chain triglycerides (MCT's) are a safe and potentially superior energy source during parenteral nutrition 13 patients were entered into a randomised cross over trial. They received either a long chain triglyceride emulsion (LCT) or a 50% medium chain (MCT)/50% LCT mixture as part of their energy supply. Nitrogen balance was significantly better when MCT/LCT was infused and the greater levels of plasma ketones and lower plasma triglyceride levels suggested that MCT was more readily metabolised in these patients. Routine haematology, biochemistry and liver function tests gave no indication of harmful side effects from MCT.

摘要

为了验证中链甘油三酯(MCT)在肠外营养期间是一种安全且可能更优质的能量来源这一假设,13名患者参与了一项随机交叉试验。他们接受长链甘油三酯乳剂(LCT)或50%中链(MCT)/50%LCT混合物作为能量供应的一部分。输注MCT/LCT时氮平衡明显更好,血浆酮水平升高和血浆甘油三酯水平降低表明MCT在这些患者中更容易被代谢。常规血液学、生物化学和肝功能检查未显示MCT有有害副作用。

相似文献

1
The metabolic consequences of infusing emulsions containing medium chain triglycerides for parenteral nutrition: a comparative study with conventional lipid.输注含中链甘油三酯的乳剂用于肠外营养的代谢后果:与传统脂质的比较研究
Ann R Coll Surg Engl. 1986 May;68(3):119-21.
2
Nitrogen sparing effect of structured triglycerides containing both medium-and long-chain fatty acids in critically ill patients; a double blind randomized controlled trial.含中链和长链脂肪酸的结构化甘油三酯对危重症患者的氮节省作用:一项双盲随机对照试验。
Clin Nutr. 2001 Feb;20(1):43-8. doi: 10.1054/clnu.2000.0156.
3
Efficacy of a mixture of medium-chain triglyceride (75%) and long-chain triglyceride (25%) fat emulsions in the nutritional management of multiple-trauma patients.中链甘油三酯(75%)与长链甘油三酯(25%)混合脂肪乳剂在多发伤患者营养管理中的疗效
Nutrition. 1995 May-Jun;11(3):275-84.
4
[Metabolic effects of medium-chain triglycerides in parenteral nutrition after surgery].[中链甘油三酯在术后肠外营养中的代谢作用]
Zhonghua Wai Ke Za Zhi. 2001 Sep;39(9):694-7.
5
[Medium-chain triglycerides metabolism and its application in total parenteral nutrition].[中链甘油三酯的代谢及其在全胃肠外营养中的应用]
Zhonghua Wai Ke Za Zhi. 1990 Dec;28(12):745-7, 783.
6
[Randomized study comparing long-chain (LCT) and medium-chain (MCT) triglycerides as caloric carriers in postoperative nutritional therapy].[比较长链(LCT)和中链(MCT)甘油三酯作为术后营养治疗中热量载体的随机研究]
Infusionsther Klin Ernahr. 1987 Apr;14(2):61-4.
7
Lipid resuscitation of bupivacaine toxicity: long-chain triglyceride emulsion provides benefits over long- and medium-chain triglyceride emulsion.布比卡因中毒的脂质复苏:长链甘油三酯乳剂优于长链和中链甘油三酯乳剂。
Anesthesiology. 2011 Dec;115(6):1219-28. doi: 10.1097/ALN.0b013e318238be73.
8
[Clinical studies with fat emulsions containing LCT and MCT].含长链甘油三酯(LCT)和中链甘油三酯(MCT)的脂肪乳剂的临床研究
Infusionsther Klin Ernahr. 1987 Sep;14 Suppl 3:38-49.
9
Improvement of graft function and animal survival by fat emulsion in liver transplant rats.脂肪乳剂改善肝移植大鼠的移植物功能及提高动物存活率。
Colloids Surf B Biointerfaces. 2007 Jan 15;54(1):25-32. doi: 10.1016/j.colsurfb.2006.05.017. Epub 2006 Jun 2.
10
Parenteral nutrition in the critically ill: use of a medium chain triglyceride emulsion.危重症患者的肠外营养:中链甘油三酯乳剂的应用
Intensive Care Med. 1993;19(2):89-95. doi: 10.1007/BF01708368.

引用本文的文献

1
Applications of Medium-Chain Triglycerides in Foods.中链甘油三酯在食品中的应用。
Front Nutr. 2022 Jun 2;9:802805. doi: 10.3389/fnut.2022.802805. eCollection 2022.
2
Parenteral nutrition in the critically ill: use of a medium chain triglyceride emulsion.危重症患者的肠外营养:中链甘油三酯乳剂的应用
Intensive Care Med. 1993;19(2):89-95. doi: 10.1007/BF01708368.
3
Comparison of medium and long chain triglyceride metabolism in intensive care patients on parenteral nutrition.重症监护病房接受肠外营养的患者中长链甘油三酯代谢的比较
Intensive Care Med. 1989;15(4):250-4. doi: 10.1007/BF00271061.

本文引用的文献

1
The toxicity of low-molecular triglycerides.低分子甘油三酯的毒性。
Acta Physiol Scand. 1957 Oct 22;40(4):338-43. doi: 10.1111/j.1748-1716.1957.tb01502.x.
2
Medium-chain triglycerides: an update.中链甘油三酯:最新进展
Am J Clin Nutr. 1982 Nov;36(5):950-62. doi: 10.1093/ajcn/36.5.950.
3
Medium chain triglycerides in parenteral nutrition.肠外营养中的中链甘油三酯。
JPEN J Parenter Enteral Nutr. 1981 Mar-Apr;5(2):115-9. doi: 10.1177/0148607181005002115.
4
Carnitine metabolism and its application in parenteral nutrition.肉碱代谢及其在肠外营养中的应用。
JPEN J Parenter Enteral Nutr. 1980 Sep-Oct;4(5):469-86. doi: 10.1177/014860718000400508.
5
Fat emulsions containing medium chain triglycerides in parenteral nutrition of intensive care patients.在重症监护患者的肠外营养中含中链甘油三酯的脂肪乳剂。
JPEN J Parenter Enteral Nutr. 1980 Jul-Aug;4(4):360-6. doi: 10.1177/014860718000400405.
6
Effect of ketone infusions on amino acid and nitrogen metabolism in man.酮输注对人体氨基酸和氮代谢的影响。
J Clin Invest. 1975 Jun;55(6):1382-90. doi: 10.1172/JCI108057.
7
Branched-chain amino acids, nitrogen excretion and injury in man.支链氨基酸、氮排泄与人体损伤
Clin Sci Mol Med. 1976 May;50(5):393-9. doi: 10.1042/cs0500393.
8
Ketosis and nitrogen excretion in undernourished surgical patients.营养不良外科患者的酮症和氮排泄
JPEN J Parenter Enteral Nutr. 1979 Sep-Oct;3(5):350-4. doi: 10.1177/014860717900300506.
9
Effects of hypercaloric glucose infusion on lipid metabolism in injury and sepsis.高热量葡萄糖输注对损伤和脓毒症脂质代谢的影响。
J Trauma. 1979 Sep;19(9):649-54. doi: 10.1097/00005373-197909000-00002.
10
Initial effect of injury on ketone bodies and other blood metabolites.损伤对酮体及其他血液代谢物的初始影响。
Lancet. 1975 Jan 4;1(7897):1-3. doi: 10.1016/s0140-6736(75)92369-7.