输注含中链甘油三酯的乳剂用于肠外营养的代谢后果：与传统脂质的比较研究
The metabolic consequences of infusing emulsions containing medium chain triglycerides for parenteral nutrition: a comparative study with conventional lipid.
作者信息
Dennison A R, Ball M, Crowe P J, White K, Hands L, Watkins R M, Kettlewell M
出版信息
Ann R Coll Surg Engl. 1986 May;68(3):119-21.
In order to test the hypothesis that medium chain triglycerides (MCT's) are a safe and potentially superior energy source during parenteral nutrition 13 patients were entered into a randomised cross over trial. They received either a long chain triglyceride emulsion (LCT) or a 50% medium chain (MCT)/50% LCT mixture as part of their energy supply. Nitrogen balance was significantly better when MCT/LCT was infused and the greater levels of plasma ketones and lower plasma triglyceride levels suggested that MCT was more readily metabolised in these patients. Routine haematology, biochemistry and liver function tests gave no indication of harmful side effects from MCT.
为了验证中链甘油三酯（MCT）在肠外营养期间是一种安全且可能更优质的能量来源这一假设，13名患者参与了一项随机交叉试验。他们接受长链甘油三酯乳剂（LCT）或50%中链（MCT）/50%LCT混合物作为能量供应的一部分。输注MCT/LCT时氮平衡明显更好，血浆酮水平升高和血浆甘油三酯水平降低表明MCT在这些患者中更容易被代谢。常规血液学、生物化学和肝功能检查未显示MCT有有害副作用。
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