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伏格特-小柳-原田病与匐行性脉络膜视网膜病变:异同点——基质性脉络膜炎临床病理学一瞥、观点及综述

Vogt-Koyanagi-Harada Disease and Birdshot Retinochoroidopathy, Similarities and Differences: A Glimpse into the Clinicopathology of Stromal Choroiditis, a Perspective and a Review.

作者信息

Elahi Sina, Herbort Carl P

机构信息

Ophthalmology, Clinique de Montchoisi, Chemin des Allinges, Lausanne, Switzerland.

Retinal and Inflammatory Eye Diseases, Centre for Ophthalmic Specialized Care (COS), Rue Charles Monnard 6, Lausanne, Switzerland.

出版信息

Klin Monbl Augenheilkd. 2019 Apr;236(4):492-510. doi: 10.1055/a-0829-6763. Epub 2019 Mar 19.

Abstract

The purpose of this work was to give a comprehensive and updated review on two primary stromal choroiditis entities, Vogt-Koyanagi-Harada disease (VKH) and birdshot retinochoroiditis (BRC). Their appraisal has become much more precise thanks to new investigational methods, such as indocyanine green angiography (ICGA) and enhanced depth imaging optical coherence tomography (EDI-OCT), which give substantially improved imaging access to the choroid. In this review, we focus on the crucial changes brought by this progress in the understanding, diagnosis, and management of these disorders. Application of these methods makes it possible to reach an early diagnosis, therefore allowing early treatment, which has led to a profound improvement in outcomes when compared to previous management.

摘要

这项工作的目的是对两种主要的基质性脉络膜炎实体——伏格特-小柳-原田病(VKH)和鸟枪弹样视网膜脉络膜炎(BRC)进行全面且更新的综述。由于新的研究方法,如吲哚菁绿血管造影(ICGA)和增强深度成像光学相干断层扫描(EDI-OCT),对它们的评估变得更加精确,这些方法能显著改善对脉络膜的成像观察。在本综述中,我们聚焦于这一进展给这些疾病的理解、诊断和管理带来的关键变化。这些方法的应用使得早期诊断成为可能,从而能够进行早期治疗,与以往的管理相比,这已使治疗结果有了显著改善。

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