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CD4细胞计数监测在HIV差异化护理和监测中的持续价值

The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance.

作者信息

Rice Brian, Boulle Andrew, Schwarcz Sandra, Shroufi Amir, Rutherford George, Hargreaves James

机构信息

Faculty of Public Health and Policy, Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Faculty of Health Sciences, Department of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.

出版信息

JMIR Public Health Surveill. 2019 Mar 20;5(1):e11136. doi: 10.2196/11136.

DOI:10.2196/11136
PMID:30892272
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6446153/
Abstract

The move toward universal provision of antiretroviral therapy and the expansion of HIV viral load monitoring call into question the ongoing value of CD4 cell count testing and monitoring. We highlight the role CD4 monitoring continues to have in guiding clinical decisions and measuring and evaluating the epidemiology of HIV. To end the HIV/AIDS epidemic, we require strategic information, which includes CD4 cell counts, to make informed clinical decisions and effectively monitor key surveillance indicators.

摘要

向普遍提供抗逆转录病毒疗法的转变以及艾滋病毒病毒载量监测的扩大，使CD4细胞计数检测和监测的持续价值受到质疑。我们强调CD4监测在指导临床决策以及测量和评估艾滋病毒流行病学方面继续发挥的作用。为了终结艾滋病毒/艾滋病流行，我们需要包括CD4细胞计数在内的战略信息，以便做出明智的临床决策并有效监测关键监测指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e920/6446153/4486113b6fce/publichealth_v5i1e11136_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e920/6446153/4486113b6fce/publichealth_v5i1e11136_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e920/6446153/4486113b6fce/publichealth_v5i1e11136_fig1.jpg

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