Division of Periodontology, Diagnostic Sciences and Dental Hygiene Ostrow School of Dentistry of USC, University of Southern California, Los Angeles, California, USA.
Periodontol 2000. 2019 Feb;79(1):233-235. doi: 10.1111/prd.12258.
Periodontology has evolved from a predominantly mechanical to a sophisticated infectious disease-based discipline. Research has paved the way for a greater understanding of the periodontal microbiome, improvement in periodontal diagnostics and therapies, and the recognition of periodontitis being associated with more than 50 systemic diseases. The etiopathology of progressive periodontitis includes active herpesviruses, specific bacterial pathogens, and proinflammatory immune responses. This article points to a role of periodontal herpesviruses in the development of systemic diseases and proposes treatment of severe periodontitis not only to avoid tooth loss, but also to reduce the risk for systemic diseases. An efficient, safe, and reliable anti-infective treatment of severe periodontitis is presented, which targets both herpesviruses and bacterial pathogens and which can be carried out in minimal time with minimal cost.
牙周病学已从以机械治疗为主发展为一门复杂的基于传染病的学科。研究为更深入地了解牙周微生物组、改善牙周病的诊断和治疗以及认识到牙周炎与 50 多种系统性疾病有关铺平了道路。进展性牙周炎的病因包括活性疱疹病毒、特定的细菌病原体和促炎免疫反应。本文指出牙周疱疹病毒在系统性疾病发展中的作用，并提出不仅要治疗严重牙周炎以避免牙齿脱落，还要降低系统性疾病的风险。本文提出了一种有效、安全和可靠的治疗严重牙周炎的方法，该方法同时针对疱疹病毒和细菌病原体，且可以在最短的时间内以最低的成本进行。
