Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, People's Republic of China.
Phys Med Biol. 2019 Apr 10;64(8):085012. doi: 10.1088/1361-6560/ab1152.
Detectors with depth encoding capability, good energy resolution and good timing resolution are required to develop high performance whole body and total body PET scanners. In this work, an 8 × 8 LYSO array with crystal size of 3 × 3 × 20 mm was fabricated by using coupling materials that included 5 mm optical glue, 9 mm triangle ESR reflector and 6 mm rectangle ESR reflector from the top to the bottom in between adjacent crystals in one direction. The LYSO array was single-ended read out by an 8 × 8 SiPM array with one-to-one coupling. Row and column summing circuit was used to read out the SiPM signals. The depth of interaction (DOI) of the detector was measured with the depth dependent light sharing between adjacent crystals while maintaining acceptable energy resolution and timing resolution. The performance of the detector module was evaluated. All crystals can be clearly resolved from the measured flood histogram. An average DOI resolution of 4.62 mm and an average timing resolution of 518 ps are obtained for events with E > 400 keV. The average energy resolution of the detector is 13.5%. This work provides a cost-effective depth encoding detector module that can be used to build high performance whole body and total body PET scanners in the future.
需要具有深度编码能力、良好的能量分辨率和良好的时间分辨率的探测器来开发高性能全身和全身 PET 扫描仪。在这项工作中，通过使用耦合材料，在一个方向上相邻晶体之间的顶部到底部依次为 5mm 光学胶、9mm 三角形 ESR 反射器和 6mm 长方形 ESR 反射器，制作了一个 8×8 的 LYSO 阵列，晶体尺寸为 3×3×20mm。LYSO 阵列通过一个 8×8 的 SiPM 阵列进行单端读取，每个 SiPM 与一个晶体耦合。使用行和列求和电路来读取 SiPM 信号。通过相邻晶体之间的深度相关光共享来测量探测器的交互深度（DOI），同时保持可接受的能量分辨率和时间分辨率。评估了探测器模块的性能。从测量的洪水直方图中可以清楚地分辨出所有的晶体。对于能量大于 400keV 的事件，获得了平均 DOI 分辨率为 4.62mm 和平均时间分辨率为 518ps。探测器的平均能量分辨率为 13.5%。这项工作提供了一种具有成本效益的深度编码探测器模块，可用于未来构建高性能全身和全身 PET 扫描仪。
