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一种使用硅光电倍增管的光共享和单端读出的深度编码 PET 探测器。

A depth-encoding PET detector that uses light sharing and single-ended readout with silicon photomultipliers.

机构信息

These authors contributed equally to this work.

出版信息

Phys Med Biol. 2018 Feb 13;63(4):045009. doi: 10.1088/1361-6560/aaa94e.

DOI:10.1088/1361-6560/aaa94e
PMID:29438101
Abstract

Detectors with depth-encoding capability and good timing resolution are required to develop high-performance whole-body or total-body PET scanners. In this work, depth-encoding PET detectors that use light sharing between two discrete crystals and single-ended readout with silicon photomultipliers (SiPMs) were manufactured and evaluated. The detectors consisted of two unpolished 3  ×  3  ×  20 mm LYSO crystals with different coupling materials between them and were read out by Hamamatsu 3  ×  3 mm SiPMs with one-to-one coupling. The ratio of the energy of one SiPM to the total energy of two SiPMs was used to measure the depth of interaction (DOI). Detectors with different coupling materials in-between the crystals were measured in the singles mode in an effort to obtain detectors that can provide good DOI resolution. The DOI resolution and energy resolution of three types of detector were measured and the timing resolution was measured for the detector with the best DOI and energy resolution. The optimum detector, with 5 mm optical glue, a 9 mm triangular ESR and a 6 mm rectangular ESR in-between the unpolished crystals, provides a DOI resolution of 2.65 mm, an energy resolution of 10.0% and a timing resolution of 427 ps for events of E  >  400 keV. The detectors simultaneously provide good DOI and timing resolution, and show great promise for the development of high-performance whole-body and total-body PET scanners.

摘要

为了开发高性能的全身或全身 PET 扫描仪,需要具有深度编码能力和良好时间分辨率的探测器。在这项工作中,制造和评估了使用两个离散晶体之间的光共享和硅光电倍增管(SiPM)进行单端读出的深度编码 PET 探测器。探测器由两个未经抛光的 3×3×20mm LYSO 晶体组成,它们之间有不同的耦合材料,并用 Hamamatsu 的 3×3mm SiPM 进行单端读出,SiPM 与晶体之间为一一对应耦合。一个 SiPM 的能量与两个 SiPM 的总能量的比值用于测量相互作用深度(DOI)。在单事件模式下测量了晶体之间具有不同耦合材料的探测器,以获得能够提供良好 DOI 分辨率的探测器。测量了三种类型的探测器的 DOI 分辨率和能量分辨率,并测量了具有最佳 DOI 和能量分辨率的探测器的时间分辨率。具有 5mm 光学胶、9mm 三角形 ESR 和 6mm 矩形 ESR 的最佳探测器,在未经抛光晶体之间,提供了 2.65mm 的 DOI 分辨率、10.0%的能量分辨率和 427ps 的时间分辨率,用于 E>400keV 的事件。这些探测器同时提供了良好的 DOI 和时间分辨率,为开发高性能的全身和全身 PET 扫描仪提供了很大的希望。

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