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短期使用类固醇在家中治疗儿童急性哮喘。

Short course of steroids in home treatment of children with acute asthma.

作者信息

Deshpande A, McKenzie S A

出版信息

Br Med J (Clin Res Ed). 1986 Jul 19;293(6540):169-71. doi: 10.1136/bmj.293.6540.169.

DOI:10.1136/bmj.293.6540.169
PMID:3089439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1340908/
Abstract

A double blind, randomised, placebo controlled study of the treatment of children with acute asthma at home showed that a three day course of prednisolone hastened improvement of both asthmatic symptoms and peak expiratory flow rates. Thus all asthmatic children who present with an acute attack should be considered for treatment with corticosteroids in addition to bronchodilators not only to prevent possible deterioration but also to speed recovery.

摘要

一项针对儿童在家中治疗急性哮喘的双盲、随机、安慰剂对照研究表明,为期三天的泼尼松龙疗程可加速哮喘症状和呼气峰值流速的改善。因此,所有出现急性发作的哮喘儿童,除支气管扩张剂外,还应考虑使用皮质类固醇进行治疗,这不仅是为了防止可能的病情恶化,也是为了加速康复。

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Short course of steroids in home treatment of children with acute asthma.短期使用类固醇在家中治疗儿童急性哮喘。
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2
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本文引用的文献

1
Emergency management of asthma in children.儿童哮喘的急诊处理
J Pediatr. 1980 Sep;97(3):346-50. doi: 10.1016/s0022-3476(80)80179-x.
2
Acute severe asthma treated without steroids.未使用类固醇治疗的急性重症哮喘
Br J Dis Chest. 1982 Jan;76(1):15-9.
3
Double-blind evaluation of methylprednisolone versus placebo for acute asthma episodes.甲泼尼龙与安慰剂治疗急性哮喘发作的双盲评估。
Pediatrics. 1983 Apr;71(4):510-14.
4
Controlled trial of slow-release aminophylline in childhood asthma: are short-term trials valid?儿童哮喘缓释氨茶碱对照试验:短期试验是否有效?
Br Med J (Clin Res Ed). 1982 Mar 20;284(6319):863-6. doi: 10.1136/bmj.284.6319.863.
5
Glucocorticoids in acute asthma. A critical controlled trial.急性哮喘中的糖皮质激素。一项关键对照试验。
Am J Med. 1983 May;74(5):845-51. doi: 10.1016/0002-9343(83)91076-8.
6
Status asthmaticus in children: a one-year study.儿童哮喘持续状态:一项为期一年的研究。
Arch Dis Child. 1979 Aug;54(8):581-6. doi: 10.1136/adc.54.8.581.