儿童哮喘持续状态：一项为期一年的研究。
Status asthmaticus in children: a one-year study.
作者信息
McKenzie S A, Edmunds A T, Godfrey S
出版信息
Arch Dis Child. 1979 Aug;54(8):581-6. doi: 10.1136/adc.54.8.581.
Abstract
50 children were admitted on 72 occasions during one year in status asthmaticus, defined as wheezing not relieved by two doses of bronchodilator 4 hours apart. At least one-third of children were hypercapnoeic on admission. They were managed with either oral prednisolone and nebulised salbutamol. Those with peak expiratory flow rates of greater than 25% expected for height were satisfactorily managed on the oral regimen. One child needed assisted ventilation. 73% were fit for discharge within 4 days and more than half of them needed a change in maintanance treatment.
摘要
在一年时间里，有50名儿童因哮喘持续状态入院72次，哮喘持续状态定义为间隔4小时使用两剂支气管扩张剂后喘息仍未缓解。至少三分之一的儿童入院时存在高碳酸血症。他们接受了口服泼尼松龙和雾化沙丁胺醇治疗。呼气峰值流速大于身高预期值25%的儿童采用口服治疗方案效果良好。有一名儿童需要辅助通气。73%的儿童在4天内适合出院，其中一半以上的儿童需要改变维持治疗方案。
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