Idachaba Samuel, Dada Oluwafemi, Abimbola Olalekan, Olayinka Olamide, Uma Akunnaya, Olunu Esther, Fakoya Adegbenro Omotuyi John
All Saints University, School of Medicine, Roseau, Dominica.
University of Medicine and Health Sciences, Basseterre, St. Kitts and Nevis, West Indies.
Open Access Maced J Med Sci. 2019 Feb 14;7(4):663-671. doi: 10.3889/oamjms.2019.104. eCollection 2019 Feb 28.
Pancreatic cancer ranks among the causes of cancer-related deaths. The average size of pancreatic cancer during diagnosis is about 31 mm and has not changed significantly over the past 30 years. Poor early diagnosis of a tumour has been attributed to the late-presenting symptoms. Over the years, improvement in the diagnosis of pancreatic cancer has been observed, and this can be linked to advancement in imaging techniques as well as the increasing knowledge of cancer history and genetics. Magnetic Resonance Imaging, Endoscopic Ultrasound, and Computer Topography are the approved imaging modalities utilised in the diagnosing of pancreatic cancer. Over the years, the management of patients with pancreatic cancer has seen remarkable improvement as reliable techniques can now be harnessed and implemented in determining the resectability of cancer. However, only about 10% of pancreatic adenocarcinomas are resectable at the time of diagnosis and will highly benefit from a microscopic margin-negative surgical resection. Overall, the failure of early tumour identification will result in considerable morbidity and mortality.
胰腺癌位列癌症相关死亡原因之中。胰腺癌在诊断时的平均大小约为31毫米，在过去30年里并未显著变化。肿瘤早期诊断不佳归因于症状出现较晚。多年来，已观察到胰腺癌诊断方面的改善，这可与成像技术的进步以及对癌症病史和遗传学知识的不断增加联系起来。磁共振成像、内镜超声和计算机断层扫描是用于诊断胰腺癌的认可成像方式。多年来，胰腺癌患者的管理有了显著改善，因为现在可以利用可靠技术来确定癌症的可切除性并加以实施。然而，在诊断时只有约10%的胰腺腺癌可切除，并且将从显微镜下切缘阴性的手术切除中极大受益。总体而言，早期肿瘤识别失败将导致相当高的发病率和死亡率。
