Nnaoma Christopher, Chika-Nwosuh Ogechukwu, Engell Christian
Department of Internal Medicine, Newark Beth Israel Medical Center, Newark, NJ, USA.
Department of Infectious Diseases, Newark Beth Israel Medical Center, Newark, NJ, USA.
Am J Case Rep. 2019 Mar 22;20:377-380. doi: 10.12659/AJCR.914640.
BACKGROUND Strongyloides stercoralis is an intestinal helminth. Parasitism is caused by penetration of the larvae through the skin. It is endemic in tropical and subtropical regions of the world and in the United States occurs in the southeastern region. It has a tendency to remain dormant or progress to a state of hyper-infection during immunosuppression. CASE REPORT We present the case of a 70-year-old Nigerian who developed fatal ARDS secondary to Strongyloides infection after been treated with steroids for treatment of autoimmune necrotizing myopathy. Despite adequate management with mechanical ventilation and appropriate antifungal therapy, the patient died on day 19 of hospitalization. CONCLUSIONS S. stercoralis is known to affect every organ in the body. ARDS is often an overlooked complication of Strongyloides hyper-infection, which is often deadly. Immediate diagnosis and treatment are important for patient survival.
背景 粪类圆线虫是一种肠道蠕虫。其感染是由幼虫经皮肤侵入引起的。该寄生虫在世界热带和亚热带地区呈地方性流行，在美国则多见于东南部地区。在免疫抑制期间，它往往会保持潜伏状态或发展为高度感染状态。病例报告 我们报告一例70岁尼日利亚男性病例，该患者因自身免疫性坏死性肌病接受类固醇治疗后，继发粪类圆线虫感染，进而发展为致命性急性呼吸窘迫综合征（ARDS）。尽管给予了机械通气及适当的抗真菌治疗，但患者仍在住院第19天死亡。结论 已知粪类圆线虫可累及人体各个器官。ARDS常常是粪类圆线虫高度感染被忽视的并发症，且往往是致命的。及时诊断和治疗对患者存活至关重要。
