Department of Electrical Engineering, National Institute of Technology Calicut, 673601, Calicut, India.
Department of Radiology, Government Medical College Kozhikode, 673008, Calicut, India.
J Med Syst. 2019 Mar 21;43(5):113. doi: 10.1007/s10916-019-1228-2.
Computer aided diagnosis using artificial intelligent techniques made tremendous improvement in medical applications especially for easy detection of tumor area, tumor type and grades. This paper presents automatic glioma tumor grade identification from magnetic resonant images using Wndchrm tool based classifier (Weighted Neighbour Distance using Compound Heirarchy of Algorithms Representing Morphology) and VGG-19 deep convolutional neural network (DNN). For experimentation, DICOM images are collected from reputed government hospital and the proposed intelligent system categorized the tumor into four grades such as low grade glioma, oligodendroglioma, anaplastic glioma and glioblastoma multiform. After preprocessing, features are extracted, optimized and then classified using Windchrm tool where the most significant features are selected on the basis of Fisher score. In the case of DNN classifier, data augmentation is also performed before applying the images into the deep learning network. The performance of the classifiers are analysed with various measures such as accuracy, precision, sensitivity, specificity and F1-score. The results showed reasonably good performance with a maximum classification accuracy of 92.86% for the Wndchrm classifier and 98.25% for VGG-19 DNN classifier. The results are also compared with similar recent works and the proposed system is found to have better performance.
基于人工智 能技术的计算机辅助诊断在医学应用中取得了巨大的进步,特别是在肿瘤区域、肿瘤类型和分级的易于检测方面。本文提出了一种使用基于加权邻域距离的分类器 (Weighted Neighbour Distance using Compound Heirarchy of Algorithms Representing Morphology, Windchrm) 和 VGG-19 深度卷积神经网络 (Deep Convolutional Neural Network, DNN) 从磁共振图像中自动识别脑胶质瘤肿瘤级别的方法。在实验中,从知名政府医院收集 DICOM 图像,然后使用智能系统将肿瘤分为四个等级:低级别胶质瘤、少突胶质细胞瘤、间变性星形细胞瘤和胶质母细胞瘤。经过预处理、提取和优化特征后,使用 Windchrm 工具进行分类,根据 Fisher 得分选择最显著的特征。在 DNN 分类器的情况下,在将图像应用于深度学习网络之前,还进行了数据扩充。通过准确性、精度、灵敏度、特异性和 F1 分数等各种指标对分类器的性能进行分析。结果表明,Windchrm 分类器的最大分类准确率为 92.86%,VGG-19 DNN 分类器的最大分类准确率为 98.25%,分类效果相当好。将结果与最近的类似工作进行比较,发现所提出的系统具有更好的性能。