Amjad Usman, Raza Asif, Fahad Muhammad, Farid Doaa, Akhunzada Adnan, Abubakar Muhammad, Beenish Hira
NED University of Engineering and Technology, Karachi, Pakistan.
Sir Syed University of Engineering and Technology, Karachi, Pakistan.
Heliyon. 2025 Jan 13;11(2):e41835. doi: 10.1016/j.heliyon.2025.e41835. eCollection 2025 Jan 30.
Machine learning has tremendous potential in acute medical care, particularly in the field of precise medical diagnosis, prediction, and classification of brain tumors. Malignant gliomas, due to their aggressive growth and dismal prognosis, stand out among various brain tumor types. Recent advancements in understanding the genetic abnormalities that underlie these tumors have shed light on their histo-pathological and biological characteristics, which support in better classification and prognosis.
This review aims to predict gene alterations and establish structured correlations among various tumor types, extending the prediction of genetic mutations and structures using the latest machine learning techniques. Specifically, it focuses on multi-modalities of Magnetic Resonance Imaging (MRI) and histopathology, utilizing Convolutional Neural Networks (CNN) for image processing and analysis.
The review encompasses the most recent developments in MRI, and histology image processing methods across multiple tumor classes, including Glioma, Meningioma, Pituitary, Oligodendroglioma, and Astrocytoma. It identifies challenges in tumor classification, segmentation, datasets, and modalities, employing various neural network architectures. A competitive analysis assesses the performance of CNN. Furthermore it also implies K-MEANS clustering to predict Genetic structure, Genes Clusters prediction and Molecular Alteration of various types and grades of tumors e.g. Glioma, Meningioma, Pituitary, Oligodendroglioma, and Astrocytoma.
CNN and KNN structures, with their ability to extract highlights in image-based information, prove effective in tumor classification and segmentation, surmounting challenges in image analysis. Competitive analysis reveals that CNN and outperform others algorithms on publicly available datasets, suggesting their potential for precise tumor diagnosis and treatment planning.
Machine learning, especially through CNN and SVM algorithms, demonstrates significant potential in the accurate diagnosis and classification of brain tumors based on imaging and histo-pathological data. Further advancements in this area hold promise for improving the accuracy and efficiency of intra-operative tumor diagnosis and treatment.
机器学习在急性医疗护理中具有巨大潜力,尤其是在脑肿瘤的精确医学诊断、预测和分类领域。恶性胶质瘤因其侵袭性生长和预后不良,在各种脑肿瘤类型中脱颖而出。最近在理解这些肿瘤潜在的基因异常方面取得的进展,揭示了它们的组织病理学和生物学特征,有助于更好地进行分类和预后评估。
本综述旨在预测基因改变,并在各种肿瘤类型之间建立结构化关联,利用最新的机器学习技术扩展基因突变和结构的预测。具体而言,它专注于磁共振成像(MRI)和组织病理学的多模态,利用卷积神经网络(CNN)进行图像处理和分析。
该综述涵盖了多种肿瘤类别(包括胶质瘤、脑膜瘤、垂体瘤、少突胶质细胞瘤和星形细胞瘤)在MRI和组织学图像处理方法方面的最新进展。它识别了肿瘤分类、分割、数据集和模态方面的挑战,采用了各种神经网络架构。一项竞争性分析评估了CNN的性能。此外,它还采用K均值聚类来预测各种类型和级别的肿瘤(如胶质瘤、脑膜瘤、垂体瘤、少突胶质细胞瘤和星形细胞瘤)的基因结构、基因簇预测和分子改变。
CNN和KNN结构能够提取基于图像的信息中的亮点,在肿瘤分类和分割中被证明是有效的,克服了图像分析中的挑战。竞争性分析表明,在公开可用的数据集上,CNN优于其他算法,表明它们在精确肿瘤诊断和治疗规划方面的潜力。
机器学习,尤其是通过CNN和支持向量机算法,在基于成像和组织病理学数据的脑肿瘤准确诊断和分类中显示出巨大潜力。该领域的进一步进展有望提高术中肿瘤诊断和治疗的准确性和效率。