采用基质辅助激光解吸电离飞行时间质谱法（MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase，MBT STAR-BL）检测产超广谱β-内酰胺酶（ESBL）的肠杆菌科细菌。
Detection of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae using the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay.
机构信息
Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
出版信息
J Microbiol Methods. 2019 May;160:154-156. doi: 10.1016/j.mimet.2019.03.019. Epub 2019 Mar 20.
The MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay, which analyzes bacterial induced hydrolysis of cefotaxime using MALDI-TOF MS, correctly identified 100.0% of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae as positive and 94.7% of non-ESBL producers as negative in 80 strains tested.
MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) 检测法使用 MALDI-TOF MS 分析细菌诱导头孢噻肟水解，在 80 株受试菌株中，正确鉴定出 100.0%的产超广谱β-内酰胺酶（ESBL）肠杆菌科细菌为阳性，94.7%的非 ESBL 产酶菌为阴性。
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