Tudose T I, Zelenetskaia V S, Kozlov G I, Pishchulin A A, Dobracheva A D
Probl Endokrinol (Mosk). 1986 May-Jun;32(3):3-7.
An increase in the prolactin basal level was detected in 8 out of 50 patients with ovarian polycystosis. A test with TRH and a simultaneous determination of the levels of prolactin, TTH, T3, T4 were used in 25 patients, of them a hyperergic reaction of prolactin to TRH was detected in 5. A correlation analysis of function of the thyroid was performed. Positive correlation between the levels of prolactin and TTH in patients with hyperprolactinemia and between a maximum increment in percentage to the initial level of TTH and prolactin in patients with a hyperergic reaction of prolactin to TRH was revealed. A conclusion was made of the common nature of disorder in the mechanisms of regulation of prolactin and thyroid function in patients with ovarian polycystosis.
50例多囊卵巢患者中,有8例检测到催乳素基础水平升高。对25例患者进行了促甲状腺激素释放激素(TRH)试验,并同时测定催乳素、促甲状腺激素(TSH)、三碘甲状腺原氨酸(T3)和甲状腺素(T4)水平,其中5例检测到催乳素对TRH呈过敏反应。进行了甲状腺功能的相关性分析。结果显示,高催乳素血症患者的催乳素水平与TSH水平之间呈正相关,催乳素对TRH过敏反应患者的TSH和催乳素相对于初始水平的最大百分比增量之间也呈正相关。得出结论:多囊卵巢患者催乳素和甲状腺功能调节机制紊乱具有共同性。