Pesotskaia P M
Probl Endokrinol (Mosk). 1985 May-Jun;31(3):54-6.
A study was made of the thyroid and hypophysis response to the administration of a summary analogous dose of prolactin injected in a single dose or in the course of 5 days. Experiments were made on female rats at the diestrus stage. The content of thyroid hormones and thyrotropic hormone (TTH) in the blood was determined by radioimmunoassay. The concentration of thyroid hormones and TTH was compared in the basal state and 30, 60, 120 and 180 min after prolactin injection. An acute prolactin administration was shown to result in an elevated TTH level on the 30th minute and T4 on the 60th minute. Five-day hyperprolactinemia caused a decrease in the content of thyroid hormones in the blood and disturbed positive correlative interrelationships between the thyroid hormones and negative ones between thyroxine and TTH. It is assumed that the preservation of a high prolactin level in the blood can maintain the hyperthyroid state.
对雌性大鼠在动情间期给予单次注射或连续5天注射相当于催乳素总剂量的药物后，甲状腺和垂体的反应进行了研究。通过放射免疫分析法测定血液中甲状腺激素和促甲状腺激素（TTH）的含量。比较了基础状态下以及注射催乳素后30、60、120和180分钟时甲状腺激素和TTH的浓度。结果显示，单次急性注射催乳素会导致第30分钟时TTH水平升高，第60分钟时T4升高。连续5天的高催乳素血症会导致血液中甲状腺激素含量降低，并扰乱甲状腺激素之间的正相关关系以及甲状腺素与TTH之间的负相关关系。据推测，血液中高催乳素水平的维持可能会保持甲状腺功能亢进状态。
