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阿尔茨海默病病史。

History of Alzheimer's Disease.

作者信息

Yang Hyun Duk, Kim Do Han, Lee Sang Bong, Young Linn Derg

机构信息

Harvard Neurology Clinic, Yongin, Korea.

Brainwise Co. Ltd., Yongin, Korea.

出版信息

Dement Neurocogn Disord. 2016 Dec;15(4):115-121. doi: 10.12779/dnd.2016.15.4.115. Epub 2016 Dec 31.

Abstract

As modern society ages rapidly, the number of people with dementia is sharply increasing. Direct medical costs and indirect social costs for dementia patients are also increasing exponentially. However, the lack of social awareness about dementia results in difficulties to dementia patients and their families. So, understanding dementia is the first step to remove or reduce the stigma of dementia patients and promote the health of our community. Alzheimer's disease is the most common form of dementia. The term, 'Alzheimer's disease' has been used for over 100 years since first used in 1910. With the remarkable growth of science and medical technologies, the techniques for diagnosis and treatment of dementia have also improved. Although the effects of the current symptomatic therapy are still limited, dramatic improvement is expected in the future through the continued research on disease modifying strategies at the earlier stage of disease. It is important to look at the past to understand the present and obtain an insight into the future. In this article, we review the etymology and history of dementia and previous modes of recognizing dementia. We also review the historical developments leading to the terminology of Alzheimer's disease.

摘要

随着现代社会迅速老龄化,痴呆症患者的数量急剧增加。痴呆症患者的直接医疗费用和间接社会成本也在呈指数级增长。然而,社会对痴呆症缺乏认识给痴呆症患者及其家庭带来了困难。因此,了解痴呆症是消除或减少对痴呆症患者的污名化并促进我们社区健康的第一步。阿尔茨海默病是最常见的痴呆症形式。自1910年首次使用以来,“阿尔茨海默病”这个术语已经使用了100多年。随着科学和医疗技术的显著发展,痴呆症的诊断和治疗技术也有所改进。尽管目前对症治疗的效果仍然有限,但通过在疾病早期阶段对疾病修饰策略的持续研究,有望在未来取得显著进展。回顾过去对于理解现在和洞察未来很重要。在本文中,我们回顾了痴呆症的词源和历史以及以往认识痴呆症的方式。我们还回顾了导致阿尔茨海默病这一术语出现的历史发展过程。

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History of Alzheimer's Disease.阿尔茨海默病病史。
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1
A presenilin 1 mutation in the first case of Alzheimer's disease.首例阿尔茨海默病患者中早老素1基因的突变
Lancet Neurol. 2013 Feb;12(2):129-30. doi: 10.1016/S1474-4422(12)70307-1. Epub 2012 Dec 14.
2
The discovery of Alzheimer's disease.阿尔茨海默病的发现。
Dialogues Clin Neurosci. 2003 Mar;5(1):101-8. doi: 10.31887/DCNS.2003.5.1/hhippius.
3
Alzheimer and his disease: a brief history.阿尔茨海默病及其历史。
Neurol Sci. 2011 Apr;32(2):275-9. doi: 10.1007/s10072-010-0454-7. Epub 2010 Dec 11.
4
Forecasting the global burden of Alzheimer's disease.预测阿尔茨海默病的全球负担。
Alzheimers Dement. 2007 Jul;3(3):186-91. doi: 10.1016/j.jalz.2007.04.381.
6
Alzheimer's discovery.阿尔茨海默病的发现。
Curr Biol. 2006 Nov 7;16(21):R906-10. doi: 10.1016/j.cub.2006.09.056.
7
Vascular dementia: a historical background.血管性痴呆:历史背景
Int Psychogeriatr. 2003;15 Suppl 1:11-3. doi: 10.1017/S1041610203008901.
9
Aloys Alzheimer, a coworker of Emil Kraepelin.阿洛伊斯·阿尔茨海默,埃米尔·克雷佩林的同事。
J Psychiatr Res. 1997 Nov-Dec;31(6):635-43. doi: 10.1016/s0022-3956(97)00035-6.
10
Auguste D and Alzheimer's disease.奥古斯特·D与阿尔茨海默病。
Lancet. 1997 May 24;349(9064):1546-9. doi: 10.1016/S0140-6736(96)10203-8.

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