Kwak Yong Tae, Yang YoungSoon, Koo Min-Seong
Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea.
Department of Neurology, Seoul Veterans Hospital, Seoul, Korea.
Dement Neurocogn Disord. 2017 Jun;16(2):33-39. doi: 10.12779/dnd.2017.16.2.33. Epub 2017 Jun 30.
Until recently, there is considerable mess regarding the nature of anxiety in dementia. However, anxiety is common in this population affecting from 8% to 71% of prevalence, and resulted in poor outcome and quality of life, even after controlling for depression. Because a presentation of anxiety in the context of dementia can be different from typical early-onset anxiety disorder, it is not easy one to identify and quantify anxiety reliably. Moreover, differentiating anxiety from the depression and/or dementia itself also can be formidable task. Anxiety gradually decreases at the severe stages of dementia and this symptom may be more common in vascular dementia than in Alzheimer's disease. Due to the lack of large randomized clinical trials, optimal treatment and the true degree of efficacy of treatment is not clear yet in this population. However, these treatments can reduce adverse impact of anxiety on patients and caregivers. This article provides a brief review for the diagnosis, evaluation and treatment of anxiety in dementia.
直到最近，关于痴呆症中焦虑症的本质仍存在相当大的混乱。然而，焦虑症在这一人群中很常见，患病率从8%到71%不等，即使在控制了抑郁症之后，也会导致不良后果和生活质量下降。由于痴呆症背景下的焦虑症表现可能与典型的早发性焦虑症不同，因此很难可靠地识别和量化焦虑症。此外，将焦虑症与抑郁症和/或痴呆症本身区分开来也是一项艰巨的任务。焦虑症在痴呆症的严重阶段会逐渐减轻，这种症状在血管性痴呆中可能比在阿尔茨海默病中更常见。由于缺乏大型随机临床试验，该人群中最佳治疗方法和治疗的真正疗效程度尚不清楚。然而，这些治疗可以减少焦虑症对患者和护理人员的不利影响。本文对痴呆症中焦虑症的诊断、评估和治疗进行了简要综述。
