Rich Tonya L, Gillick Bernadette T
Department of Rehabilitation Medicine, Division of Rehabilitation Science, University of Minnesota, 420 Delaware Street SE, MMC 388, Minneapolis, MN 55455, USA.
Brain Sci. 2019 Mar 22;9(3):69. doi: 10.3390/brainsci9030069.
The 10/20 electroencephalogram (EEG) measurements system often guides electrode placement for transcranial direct current stimulation (tDCS), a form of non-invasive brain stimulation. One targeted region of the brain is the primary motor cortex (M1) for motor recovery after stroke, among other clinical indications. M1 is identified by C3 and C4 of the 10/20 EEG system yet the reliability of 10/20 EEG measurements by novice research raters is unknown. We investigated the reliability of the 10/20 EEG measurements for C3 and C4 in 25 adult participants. Two novice raters were assessed for inter-rater reliability. Both raters received two hours of instruction from a registered neurodiagnostic technician. One of the raters completed the measurements across two testing days for intra-rater reliability. Relative reliability was determined using the intraclass coefficient (ICC) and absolute reliability. We observed a low to fair inter and intra-rater ICC for motor cortex measurements. The absolute reliability was <1.0 cm by different novice raters and on different days. Although a low error was observed, consideration of the integrity of the targeted region of the brain is critical when designing tDCS interventions in clinical populations who may have compromised brain structure, due to a lesion or altered anatomy.
10/20脑电图（EEG）测量系统常用于指导经颅直流电刺激（tDCS）的电极放置，tDCS是一种非侵入性脑刺激形式。大脑的一个目标区域是主要运动皮层（M1），用于中风后运动功能恢复以及其他临床适应症。在10/20 EEG系统中，M1由C3和C4标识，但新手研究评分者进行10/20 EEG测量的可靠性尚不清楚。我们调查了25名成年参与者中C3和C4的10/20 EEG测量的可靠性。评估了两名新手评分者的评分者间可靠性。两名评分者均接受了注册神经诊断技术人员两小时的指导。其中一名评分者在两个测试日完成测量以评估评分者内可靠性。使用组内相关系数（ICC）和绝对可靠性来确定相对可靠性。我们观察到运动皮层测量的评分者间和评分者内ICC为低到中等。不同新手评分者在不同日期的绝对可靠性<1.0厘米。尽管观察到误差较小，但在为可能因病变或解剖结构改变而脑结构受损的临床人群设计tDCS干预措施时，考虑大脑目标区域的完整性至关重要。
