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一项针对以患者为导向的研究的自评衰弱指数和状态的提案。

A proposal for a self-rated frailty index and status for patient-oriented research.

作者信息

Chao Yi-Sheng, McGolrick Danielle, Wu Chao-Jung, Wu Hsing-Chien, Chen Wei-Chih

机构信息

Canadian Agency for Drugs and Technologies in Health, Ottawa, Canada.

Département d'informatique, Université du Québec à Montréal, Montréal, Canada.

出版信息

BMC Res Notes. 2019 Mar 25;12(1):172. doi: 10.1186/s13104-019-4206-3.

Abstract

OBJECTIVE

Frailty indices are important predictors of major health outcomes, but mostly designed by and for researchers and specialists. Three of the most commonly used theory-based indices are composite measures that are subject to arbitrary assumptions and biases introduced due to data processing. A complicated index can be simplified with fewer items. The theory-based frailty indices are not optimal and neglect patients' perspectives. This study aims to compare different definitions of frailty and propose a self-rated measure of frailty index and status.

RESULTS

Frailty was defined differently by laypeople and researchers/clinicians. Patients' and laypeople's perspectives seemed neglected. Existing frailty indices had shortcomings related to the use of composite measures, assumptions of frailty theories, and the lack of novel information. To avoid these shortcomings, we suggested asking individuals "on a scale of 0 to 10, how frail do you think you are?" and "by answering yes or no, do you consider yourself to be frail?" to determine frailty on continuous and dichotomous scales respectively. However, there will be other issues emerging with these new measures, such as the need for feasibility and validity studies, as well as acceptability by researchers.

摘要

目的

衰弱指数是主要健康结局的重要预测指标,但大多是由研究人员和专家设计并为其所用。三种最常用的基于理论的指数是综合测量指标,在数据处理过程中容易受到任意假设和偏差的影响。一个复杂的指数可以用较少的项目进行简化。基于理论的衰弱指数并非最优,且忽视了患者的观点。本研究旨在比较衰弱的不同定义,并提出一种自我评定的衰弱指数和状态测量方法。

结果

外行人与研究人员/临床医生对衰弱的定义不同。患者和外行人的观点似乎被忽视了。现有的衰弱指数在综合测量指标的使用、衰弱理论的假设以及缺乏新信息方面存在缺陷。为避免这些缺陷,我们建议询问个体“从0到10分,你认为自己有多衰弱?”以及“通过回答是或否,你认为自己是衰弱的吗?”,分别在连续和二分尺度上确定衰弱程度。然而,这些新的测量方法会出现其他问题,例如需要进行可行性和有效性研究,以及研究人员的可接受性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d171/6434809/cbafbe837832/13104_2019_4206_Fig1_HTML.jpg

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