Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Nat Rev Neurosci. 2019 Jun;20(6):346-363. doi: 10.1038/s41583-019-0153-1.
How the brain computes accurate estimates of our self-motion relative to the world and our orientation relative to gravity in order to ensure accurate perception and motor control is a fundamental neuroscientific question. Recent experiments have revealed that the vestibular system encodes this information during everyday activities using pathway-specific neural representations. Furthermore, new findings have established that vestibular signals are selectively combined with extravestibular information at the earliest stages of central vestibular processing in a manner that depends on the current behavioural goal. These findings have important implications for our understanding of the brain mechanisms that ensure accurate perception and behaviour during everyday activities and for our understanding of disorders of vestibular processing.
大脑如何计算我们相对于世界的自身运动和相对于重力的方向的精确估计，以确保精确的感知和运动控制，这是一个基本的神经科学问题。最近的实验表明，前庭系统在日常活动中使用特定途径的神经表示来编码这些信息。此外，新的发现已经确立，前庭信号在中央前庭处理的最早阶段以依赖于当前行为目标的方式与前庭外信息选择性地组合。这些发现对我们理解确保在日常活动中进行精确感知和行为的大脑机制以及对我们理解前庭处理障碍具有重要意义。
