Nguyen Anh Tuan Le, Le Xuan Thanh Thi, Do Toan Thanh Thi, Nguyen Cuong Tat, Hoang Nguyen Long, Tran Bach Xuan, Le Huong Thi
Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Institute for Global Health Innovations, Duy Tan University, Da Nang, Vietnam.
Biomed Res Int. 2019 Feb 21;2019:9154918. doi: 10.1155/2019/9154918. eCollection 2019.
Hepatitis B virus (HBV) vaccine is a critical approach to prevent HBV transmission from mother to child. However, despite high HBV prevalence, evidence about the preference of women of productive age for HBV vaccine in Vietnam was constrained. This study aims to explore the preference and willingness to pay (WTP) for the HBV vaccine in Vietnamese women in productive age.
A cross-sectional study was conducted in Hanoi in April 2016. A structured questionnaire was used to collect information about respondents' socioeconomic status and knowledge about HBV vaccination. A contingent valuation approach was employed to measure the WTP for the HBV vaccine. Logistic and interval regressions were used to determine the associated factors.
Among 807 women, 80.8% were willing to have the vaccine injected which had the average price of 108,600 VND (95% CI, 97,580 VND-119,570 VND). Participants not suffering any diseases during pregnancy were more likely to be willing to pay for the HBV vaccine (OR = 3.41, 95% CI = 1.73-6.70). Not having the antenatal examination at central hospitals and working as farmers/workers were positively correlated with willingness to pay for this vaccine, while the number of children of respondents had a negative correlation with WTP.
Our sampled women expressed a high willingness to pay for the vaccine. The price people were willing to pay for the vaccine, however, is equal to half of the actual price. These findings implied needs for better targeted public education interventions about HBV and the involvement of local medical staffs and the media in providing information. Efforts to reduce the price of the vaccine should also be warranted for scaling-up the coverage of this vaccine.
乙肝疫苗是预防乙肝病毒母婴传播的关键措施。然而，尽管越南乙肝病毒感染率很高，但关于育龄妇女对乙肝疫苗偏好的证据却很有限。本研究旨在探讨越南育龄妇女对乙肝疫苗的偏好及支付意愿（WTP）。
2016年4月在河内进行了一项横断面研究。采用结构化问卷收集受访者的社会经济状况及乙肝疫苗接种知识信息。运用条件估值法测量乙肝疫苗的支付意愿。采用逻辑回归和区间回归确定相关因素。
在807名妇女中，80.8%愿意接种疫苗，疫苗平均价格为108,600越南盾（95%置信区间，97,580越南盾 - 119,570越南盾）。孕期未患任何疾病的参与者更有可能愿意为乙肝疫苗付费（OR = 3.41，95%置信区间 = 1.73 - 6.70）。未在中心医院进行产前检查以及从事农民/工人工作与支付该疫苗的意愿呈正相关，而受访者子女数量与支付意愿呈负相关。
我们抽样的妇女对疫苗表现出较高的支付意愿。然而，人们愿意为疫苗支付的价格仅为实际价格的一半。这些结果表明需要针对乙肝进行更有针对性的公众教育干预，并让当地医务人员和媒体参与提供信息。为扩大该疫苗的接种覆盖范围，还应努力降低疫苗价格。
