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狼疮抗凝物与肝静脉血栓形成(布加综合征)。三例报告并文献复习

'Lupus' anticoagulant and thrombosis of the hepatic veins (Budd-Chiari syndrome). Report of three patients and review of the literature.

作者信息

Van Steenbergen W, Beyls J, Vermylen J, Fevery J, Marchal G, Desmet V, De Groote J

出版信息

J Hepatol. 1986;3(1):87-94. doi: 10.1016/s0168-8278(86)80151-9.

Abstract

Three patients with Budd-Chiari syndrome in association with the 'lupus' anticoagulant are described. This anticoagulant was looked for in our patients with an otherwise idiopathic hepatic venous thrombosis because of the presence of a pronounced thrombocytopenia, a prolonged activated partial thromboplastin time or a history of repeated abortions and deep leg vein thrombosis, respectively. An active search for the 'lupus' anticoagulant should be performed to lower the percentage of apparently idiopathic cases of Budd-Chiari syndrome.

摘要

本文描述了3例布加综合征合并“狼疮”抗凝物的患者。由于分别存在明显的血小板减少、活化部分凝血活酶时间延长或反复流产及下肢深静脉血栓形成病史,我们对其他方面原因不明的肝静脉血栓形成患者进行了“狼疮”抗凝物检测。应积极检测“狼疮”抗凝物,以降低布加综合征明显原因不明病例的比例。

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