Yu Xudong D, Wang Jisheng S, Zuo Guang, Wang Xin, Ge Fuxing, Wu Songli, Lim Jingyang, Shang Jianwei, Zhang Yaosheng
Graduate School of Beijing University of Chinese Medicine.
Department of Andrology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing.
Medicine (Baltimore). 2019 Mar;98(13):e14928. doi: 10.1097/MD.0000000000014928.
Diabetic mellitus erectile dysfunction (DMED) refers to erectile dysfunction (ED) secondary to diabetes. As people's lifestyle changes and the population ages, the incidence of DMED continues to increase. Many clinical trials have proven that Chinese medicine has a significant effect in the treatment of DMED. In this systematic review, we aim to evaluate the effectiveness and safety of traditional Chinese medicine (TCM) for DMED.
We will search PubMed, Cochrane Library, AMED, EMbase, WorldSciNet; Nature, Science online and China Journal Full-text Database, China Biomedical Literature CD-ROM Database, and related randomized controlled trials included in the China Resources Database. The time is limited from the construction of the library to February, 2019.We will use the criteria provided by Cochrane 5.1.0 for quality assessment and risk assessment of the included studies, and use the Revman 5.3 and Stata13.0 software for meta-analysis of the effectiveness, recurrence rate, and symptom scores of DMED.
This systematic review will evaluate the efficacy and safety of TCM for treating Diabetic mellitus erectile dysfunction. Because all of the data used in this systematic review and meta-analysis has been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process trial.
糖尿病性勃起功能障碍（DMED）是指继发于糖尿病的勃起功能障碍（ED）。随着人们生活方式的改变和人口老龄化，DMED的发病率持续上升。许多临床试验已证明中药在治疗DMED方面有显著疗效。在本系统评价中，我们旨在评估中药治疗DMED的有效性和安全性。
我们将检索PubMed、Cochrane图书馆、AMED、EMbase、WorldSciNet；《自然》《科学》在线版以及中国期刊全文数据库、中国生物医学文献光盘数据库，以及华润数据库中纳入的相关随机对照试验。检索时间范围为各数据库建库至2019年2月。我们将使用Cochrane 5.1.0提供的标准对纳入研究进行质量评估和风险评估，并使用Revman 5.3和Stata13.0软件对DMED的有效性、复发率和症状评分进行荟萃分析。
本系统评价将评估中药治疗糖尿病性勃起功能障碍的疗效和安全性。由于本系统评价和荟萃分析中使用的所有数据均已发表，因此本评价无需伦理批准。此外，在评价过程中所有数据将进行匿名分析。
