Oh Hyun-Min, Kim Chul-Hyun, Kim Ae-Ryoung
Department of Rehabilitation Medicine, Kyungpook National University Hospital.
Department of Rehabilitation Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea.
Medicine (Baltimore). 2019 Mar;98(13):e14990. doi: 10.1097/MD.0000000000014990.
Complex regional pain syndrome (CRPS) usually occurs after trauma and surgery but can also occur spontaneously. There are various known pathophysiology and treatment protocols for CRPS. However, there is no established treatment guideline. Although physical therapy is known as the first line treatment for CRPS, performing physical therapy is difficult due to severe pain. This case reports the first case with positive effect of physical therapy under sedation that allowed early physical therapy.
A 19-year old female had her right elbow area slightly hit by someone else, after which it began to swell and become more painful. Active and passive range of motion (ROM) of the right upper extremity gradually decreased through 3 months, and pain and edema worsened.
She had allodynia, nonpitting edema, temperature asymmetry, and trophic change in fingernails in the right upper extremity, which met the diagnostic criteria for CRPS. In the 3-phase bone scan, which is a specific tool to diagnose CRPS, there was trace uptake increase in the right elbow and wrist, indicating possibility of CRPS.
Despite conventional treatments such as pharmacologic and interventional therapies, neither pain nor edema subsided. Pain was so severe that it was impossible to apply physical therapy. Therefore, the patient underwent passive ROM exercise in the right upper extremity under sedation for 30 minutes, which was relatively easier due to decreased pain. After 2 days of passive ROM exercise under sedation, the patient was able to receive passive ROM exercise twice daily without sedation for 18 days.
After 20 days of passive ROM exercise, including 2 days of passive ROM exercise under sedation, the circumference of her right hand decreased by 5 cm, wrist 2 cm, and elbow 6 cm compared to the initial measurement. Numeric pain rating scale improved from 9 to 3, and her manual muscle test marked fair plus from trace, Jebsen-Taylor hand function test score 43 from 0.
This case suggests that passive ROM exercise under sedation may be a successful alternative as a treatment when exercise, currently known as a treatment to CRPS, is impossible.
复杂性区域疼痛综合征(CRPS)通常在创伤和手术后发生,但也可能自发出现。CRPS有多种已知的病理生理学和治疗方案。然而,尚无既定的治疗指南。尽管物理治疗被认为是CRPS的一线治疗方法,但由于疼痛严重,进行物理治疗很困难。本病例报告了首例在镇静下进行物理治疗取得积极效果的病例,这使得早期物理治疗成为可能。
一名19岁女性右肘部被他人轻微撞击,之后该部位开始肿胀并疼痛加剧。在3个月的时间里,右上肢的主动和被动活动范围(ROM)逐渐减小,疼痛和水肿加重。
她右上肢存在痛觉过敏、非凹陷性水肿、温度不对称以及指甲的营养改变,符合CRPS的诊断标准。在诊断CRPS的特定工具三相骨扫描中,右肘和腕部有微量摄取增加,提示可能患有CRPS。
尽管采用了药物和介入治疗等传统治疗方法,但疼痛和水肿均未消退。疼痛非常严重,以至于无法进行物理治疗。因此,患者在镇静下进行了30分钟的右上肢被动ROM练习,由于疼痛减轻,这相对容易一些。在镇静下进行2天的被动ROM练习后,患者能够在无镇静的情况下每天接受2次被动ROM练习,持续18天。
在包括2天镇静下被动ROM练习在内的20天被动ROM练习后,与初始测量相比,她右手的周长减少了5厘米,手腕减少了2厘米,肘部减少了6厘米。数字疼痛评分从9分提高到3分,她的徒手肌力测试从痕迹量显著提高到中等偏上,Jebsen - Taylor手功能测试得分从0分提高到43分。
本病例表明,当目前已知的CRPS治疗方法——运动无法进行时,镇静下的被动ROM练习可能是一种成功的替代治疗方法。