Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Avenida Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico.
Departamento de Nutrición Humana, Centro de Investigación en Alimentación y Desarrollo, A.C. Astiazarán Rosas No. 46. Col. La Victoria, Hermosillo, 83304, Sonora, Mexico.
Res Microbiol. 2019 Jun-Aug;170(4-5):235-241. doi: 10.1016/j.resmic.2019.03.001. Epub 2019 Mar 25.
A weekly conference series paired with lectures entitled "Microbiome-MX: exploring the Microbiota and Microbiome Research in Mexico" was organized to provide a multidisciplinary overview of the most recent research done in Mexico using high-throughput sequencing. Scientists and postgraduate students from several disciplines such as microbiology, bioinformatics, virology, immunology, nutrition, and medical genomics gathered to discuss state of the art in each of their respective subjects of expertise, as well as advances, applications and new opportunities on microbiota/microbiome research. In particular, high-throughput sequencing is a crucial tool to understand the challenges of a megadiverse developing country as Mexico, and moreover to know the scientific capital and capabilities available for collaboration. The conference series addressed three main topics important for Mexico: i) the complex role of microbiota in health and prevalent diseases such as obesity, diabetes, inflammatory bowel disease, tuberculosis, HIV, autoimmune diseases and gastric cancer; ii) the use of local, traditional and prehispanic products as pre/probiotics to modulate the microbiota and improve human health; and iii) the impact of the microbiota in shaping the biodiversity of economically important terrestrial and marine ecosystems. Herein, we summarize the contributions that Mexican microbiota/microbiome research is making to the global trends, describing the highlights of the conferences and lectures, rather than a review of the state-of-the-art of this research. This meeting report also presents the efforts of a multidisciplinary group of scientist to encourage collaborations and bringing this research field closer for younger generations.
一个名为“微生物组-MX:探索墨西哥的微生物群和微生物组研究”的每周会议系列与讲座相结合,旨在提供一个多学科的概述,介绍使用高通量测序在墨西哥进行的最新研究。来自微生物学、生物信息学、病毒学、免疫学、营养学和医学基因组学等多个学科的科学家和研究生聚集在一起,讨论各自专业领域的最新进展,以及在微生物组/微生物组研究方面的应用和新机遇。特别是,高通量测序是理解墨西哥这样一个多样化发展中国家面临的挑战的关键工具,此外还可以了解可供合作的科学资本和能力。该会议系列涵盖了对墨西哥很重要的三个主题:i)微生物群在肥胖症、糖尿病、炎症性肠病、结核病、HIV、自身免疫性疾病和胃癌等常见疾病中的复杂作用;ii)利用本地、传统和前西班牙裔产品作为预/益生菌来调节微生物群并改善人类健康;iii)微生物群在塑造陆地和海洋生态系统的生物多样性方面的影响。在此,我们总结了墨西哥微生物组/微生物组研究对全球趋势的贡献,描述了会议和讲座的重点,而不是对该研究领域的最新进展进行综述。本会议报告还介绍了一个多学科科学家小组为鼓励合作和让年轻一代更接近这一研究领域所做的努力。