Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.
Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.
Virus Res. 2019 May;265:150-155. doi: 10.1016/j.virusres.2019.03.022. Epub 2019 Mar 25.
An outbreak in the Caucasus in 2007 initiated the spread of ASFV through Russia and Eastern Europe, subsequently affecting Ukraine, Belarus, Poland, the Baltic States, the Czech Republic, Moldova, Romania and Bulgaria. The declaration of outbreaks in China and Central Europe in August 2018, definitely confirms the serious threat that the extension of ASF represents for the global swine industry and the environment. Despite the efforts of several groups to generate a vaccine against ASFV, currently only control and eradication measures are available based mainly on the early detection and implementation of strict sanitary procedures, including the mass slaughter of animals, both domestic and wild boar. However, the rapid spread of the disease shows that these actions are clearly insufficient to control the current pandemic situation, and the development of a vaccine is urgently required.
2007 年在高加索地区发生的疫情导致非洲猪瘟病毒通过俄罗斯和东欧传播，随后影响了乌克兰、白俄罗斯、波兰、波罗的海国家、捷克共和国、摩尔多瓦、罗马尼亚和保加利亚。2018 年 8 月中国和中欧地区宣布发生疫情，这明确证实了 ASF 的蔓延对全球养猪业和环境构成的严重威胁。尽管有几个研究小组努力研制针对 ASF 的疫苗，但目前仅可采取控制和根除措施，主要基于早期检测和实施严格的卫生程序，包括大规模扑杀动物，包括家养和野猪。然而，该疾病的迅速传播表明，这些行动显然不足以控制当前的大流行情况，迫切需要开发疫苗。
