Hambidge K M
Acta Paediatr Scand Suppl. 1986;323:52-8.
A wide spectrum of zinc deficiency states has been recognized in the weanling. Severe zinc deficiency affects most organ systems and causes a wide variety of clinical manifestations; these occur only in special circumstances. Zinc deficiency of intermediate severity has been reported in malnourished infants, in whom it may contribute to the clinical manifestations and limit the rate of recovery from protein energy malnutrition. Results of randomized, controlled studies of dietary zinc supplementation in Denver indicate that mild nutritional zinc deficiency is one cause of failure to thrive. Better laboratory indices for the determination of mild zinc deficiency are needed before the epidemiology of this syndrome can be understood. Quantitative data on zinc absorption from different weanling diets are required before it will be possible to determine the adequacy of zinc intake.
断奶期婴儿中已发现多种锌缺乏状态。严重锌缺乏会影响大多数器官系统，并引发多种临床表现；但这些情况仅在特殊情形下出现。中度锌缺乏在营养不良的婴儿中已有报道，它可能会导致临床表现，并限制蛋白质能量营养不良的恢复速度。在丹佛进行的关于膳食补充锌的随机对照研究结果表明，轻度营养性锌缺乏是发育不良的一个原因。在了解该综合征的流行病学之前，需要更好的实验室指标来测定轻度锌缺乏。在能够确定锌摄入量是否充足之前，需要有关不同断奶期饮食中锌吸收的定量数据。
