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资源有限环境下烧伤患者院内病死率的相关入院因素:南非成人烧伤中心的一项为期两年的回顾性调查。

Admission factors associated with the in-hospital mortality of burns patients in resource-constrained settings: A two-year retrospective investigation in a South African adult burns centre.

机构信息

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.

Division of Emergency Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Bellville, South Africa; Division of Emergency Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

出版信息

Burns. 2019 Sep;45(6):1462-1470. doi: 10.1016/j.burns.2019.03.005. Epub 2019 Mar 28.

DOI:10.1016/j.burns.2019.03.005
PMID:30928024
Abstract

OBJECTIVE

Little is known concerning the factors associated with in-hospital mortality of trauma patients in resource-constrained settings, not least in burns centres. We investigated this question in the adult burns centre at Tygerberg Hospital in Cape Town. We further assessed whether the Abbreviated Burn Severity Index (ABSI) is an accurate predictive score of mortality in this setting.

METHODS

Medical records of all patients admitted with fresh burns over a two-year period (2015 and 2016) were scrutinized to obtain data on patient, injury and admission-related characteristics. Association with in-hospital mortality was investigated for flame burns using logistic regressions and expressed as odds ratios (ORs). The mortality prediction of the ABSI score was assessed using sensitivity and specificity analyses.

RESULTS

Overall the in-hospital mortality was 20.4%. For the 263 flame burns, while crude ORs suggested gender, burn depth, burn size, inhalation injury, and referral status were all individually significantly associated with mortality, only the association with female gender, not being referred and burn size remained significant after adjustments (adjusted ORs = 3.79, 2.86 and 1.11 (per percentage increase in size) respectively). For the ABSI score, sensitivity and specificity were 84% and 86% respectively.

CONCLUSION

In this specialised centre, mortality occurs in one in five patients. It is associated with a few clinical parameters, and can be predicted using the ABSI score.

摘要

目的

在资源有限的环境下,对于创伤患者的院内死亡率相关因素知之甚少,尤其是在烧伤中心。我们在开普敦泰格伯格医院的成人烧伤中心调查了这一问题。我们进一步评估了简化烧伤严重程度指数(ABSI)在这一环境下是否是死亡率的准确预测评分。

方法

对在两年期间(2015 年和 2016 年)因新鲜烧伤入院的所有患者的病历进行仔细检查,以获取患者、损伤和入院相关特征的数据。使用逻辑回归对火焰烧伤的院内死亡率进行关联分析,并表示为比值比(OR)。使用灵敏度和特异性分析评估 ABSI 评分的死亡率预测。

结果

总体而言,院内死亡率为 20.4%。对于 263 例火焰烧伤,虽然粗 OR 表明性别、烧伤深度、烧伤面积、吸入性损伤和转诊状态均与死亡率单独相关,但在调整后,只有女性性别、未转诊和烧伤面积与死亡率的关联仍然显著(调整后的 OR 分别为 3.79、2.86 和 1.11(每增加 1%的面积))。对于 ABSI 评分,灵敏度和特异性分别为 84%和 86%。

结论

在这个专门的中心,每五个患者中就有一个死亡。它与几个临床参数相关,可以使用 ABSI 评分进行预测。

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