Awotidebe Taofeek O, Adeyeye Victor O, Adedoyin Rufus A, Ogunyemi Suraj A, Oke Kayode I, Ativie Rita N, Adeola Goodness B, Akindele Mukadas O, Balogun Michael O
Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
Hong Kong Physiother J. 2016 Nov 22;36:17-24. doi: 10.1016/j.hkpj.2016.10.001. eCollection 2017 Jun.
Adequate sleep improves physical and mental alertness. However, there is a dearth of empirical data on functional capacity (FC) and sleep quality (SpQ) in patients with chronic heart failure (CHF).
This study investigated the relationship between FC and SpQ of patients with CHF and apparently healthy controls (HCs).
This case-control study recruited 50 patients with CHF whose left ventricular ejection fraction (LVEF) was <40%, attending cardiac clinics of selected government hospitals in Osun State. Furthermore, 50 age- and sex-matched healthy individuals were recruited as controls. Socio-demographic characteristics and cardiovascular parameters were assessed. The FC (VO max) and SpQ were assessed using the 6-minute walk test (6-MWT) and Pittsburgh Sleep Quality Index (PSQI), respectively. Data were analysed using descriptive and inferential statistics. Alpha level was set at < 0.05.
Patients had a significantly lower FC and poorer SpQ than HCs, 4.6 ± 0.5 versus 11.3 ± 1.6 mL/kg/min ( = -3.452; = 0.001) and 8.74 ± 1.6 versus 3.8 ± 1.3 ( = -5.371; = 0.001), respectively. HCs were about five times more likely to walk longer distance [odds ratio (OR), 4.8; confidence interval (CI), 2.0-11.1] and had a better heart rate (OR, 2.8; CI, 1.4-5.3) than patients. SpQ had a significant negative correlation with FC of patients ( = -0.362; = 0.001) but a significant positive correlation with HCs ( = 0.481; = 0.041). Furthermore, there were significant correlations between FC and body mass index in both groups (CHF: = 0.247, = 0.022; HCs: = 0.321, = 0.040).
Patients with heart failure demonstrated lower functional capacity and poorer sleep quality.
充足的睡眠可提高身体和精神的警觉性。然而，关于慢性心力衰竭（CHF）患者的功能能力（FC）和睡眠质量（SpQ）的实证数据匮乏。
本研究调查了CHF患者与明显健康的对照者（HCs）的FC和SpQ之间的关系。
本病例对照研究招募了50名左心室射血分数（LVEF）<40%的CHF患者，这些患者来自奥孙州选定政府医院的心脏科门诊。此外，招募了50名年龄和性别匹配的健康个体作为对照。评估了社会人口学特征和心血管参数。分别使用6分钟步行试验（6-MWT）和匹兹堡睡眠质量指数（PSQI）评估FC（最大摄氧量）和SpQ。使用描述性和推断性统计分析数据。设定α水平<0.05。
患者的FC显著低于HCs，SpQ也比HCs差，分别为4.6±0.5与11.3±1.6 mL/kg/min（t=-3.452；p=0.001）和8.74±1.6与3.8±1.3（t=-5.371；p=0.001）。与患者相比，HCs步行更长距离的可能性约为患者的五倍[优势比（OR），4.8；置信区间（CI），2.0 - 11.1]，且心率更好（OR，2.8；CI，1.4 - 5.3）。SpQ与患者的FC呈显著负相关（r=-0.362；p=0.001），但与HCs呈显著正相关（r=0.481；p=
