Department of Community Nutrition, Student Research Committee, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Nutrition, School of Health, Zabol University of Medical Sciences, Zabol, Iran.
Complement Ther Med. 2019 Apr;43:131-139. doi: 10.1016/j.ctim.2019.01.018. Epub 2019 Jan 24.
BACKGROUND & OBJECTIVE(S): Obesity is a worldwide epidemic and a common medical condition associated with a variety of chronic diseases. Cereal beta-glucans are soluble fibers with potential health benefits. A number of randomized controlled trials (RCTs) have investigated the effect of cereal beta-glucan consumption on weight, but these results have not been summarized in a meta-analysis. The purpose of this study was to investigate the effect of cereal beta-glucan consumption on body weight, body mass index, waist circumference and a total energy intake.
Studies were identified using MEDLINE/PubMed, Scopus and Cochrane databases. Screening of relevant articles and references was carried out until December 2018. There were no language restrictions. This systematic review and meta-analysis was performed using the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Twenty eligible studies were identified and analyzed. Our study found a significant reduction in body weight and body mass index (BMI) following beta-glucan consumption (weighted mean difference [WMD]: -0.77 kg, 95% CI: -1.49, -0.04) and (WMD: -0.62 kg/cm, 95% CI: -1.04, -0.21), respectively. There was no significant effect on waist circumference and energy intake. A subgroup analysis showed that a beta-glucan dose of ≥ 4 g/day lead to an increase in energy intake.
The findings of this study indicates that cereal beta-glucan consumption seems to decrease body weight and BMI, but has no effect on waist circumference and energy intake.
肥胖是一种全球性的流行疾病，也是与多种慢性疾病相关的常见病症。谷物β-葡聚糖是一种具有潜在健康益处的可溶性纤维。多项随机对照试验（RCT）已经研究了谷物β-葡聚糖的摄入对体重的影响，但这些结果尚未在荟萃分析中进行总结。本研究旨在调查谷物β-葡聚糖的摄入对体重、体重指数、腰围和总能量摄入的影响。
使用 MEDLINE/PubMed、Scopus 和 Cochrane 数据库来确定研究。对相关文章和参考文献进行筛选，直到 2018 年 12 月。没有语言限制。本系统评价和荟萃分析使用了系统评价和荟萃分析报告的首选项目（PRISMA）指南。
确定了 20 项符合条件的研究进行分析。我们的研究发现，β-葡聚糖摄入后体重和体重指数（BMI）显著降低（加权均数差[WMD]：-0.77kg，95%置信区间[CI]：-1.49，-0.04）和（WMD：-0.62kg/cm，95%CI：-1.04，-0.21）。腰围和能量摄入没有显著影响。亚组分析表明，β-葡聚糖剂量≥4g/天会导致能量摄入增加。
本研究的结果表明，谷物β-葡聚糖的摄入似乎可以降低体重和 BMI，但对腰围和能量摄入没有影响。
