员工持续存在非特异性室内空气相关健康投诉的与健康相关的生活质量。
Health-related quality among life of employees with persistent nonspecific indoor-air-associated health complaints.
机构信息
Finnish Institute of Occupational Health, Helsinki, Finland; Department of Health, National Institute for Health and Welfare, Finland; Department of Psychology and Logopedics, University of Helsinki, Finland.
Finnish Institute of Occupational Health, Helsinki, Finland.
出版信息
J Psychosom Res. 2019 Jul;122:112-120. doi: 10.1016/j.jpsychores.2019.03.181. Epub 2019 Mar 25.
OBJECTIVE
Nonspecific health complaints associated with indoor air are common in work environments. In some individuals, symptoms become persistent without an adequate explanation. The aim was to study factors that associate with the health-related quality of life (HRQoL) of employees with persistent, nonspecific indoor-air-related symptomatology.
METHODS
We present baseline results of a randomized controlled trial of interventions targeted on the HRQoL of the employees with indoor-air-associated nonspecific symptoms. The main participant-inclusion criterion was the presence of persistent indoor-air-related multiorgan symptoms with no known pathophysiological or environment-related explanation. As a comparison for participants´ HRQoL (n = 52) we used data from the general-population Health 2011 study (BRIF8901) including information on subjects matched to the participants´ working status and age and subjects with asthma, anxiety or depressive disorder, or other chronic conditions with work disability.
RESULTS
The participants showed greater and a clinically significant impairment of HRQoL [M = 0.83, SE = 0.013] than individuals from the general population [M = 0.95, SE = 0.001, p < .001, Hedges´ g = 2.33] and those with asthma [M = 0.93, SE = 0.005, p < .001, Hedges´ g = 1.46], anxiety and depressive disorder [M = 0.89, SE = 0.006, p < .001, Hedges´ g = 0.73], or a chronic condition with work disability [M = 0.91, SE = 0.003, p < .001, Hedges´ g = 1.11]. Prevalent symptoms of depression, anxiety, and insomnia and poor recovery from work were associated with a poor HRQoL.
CONCLUSIONS
Individuals with nonspecific indoor-air-associated symptoms have a poorer HRQoL than individuals in the general population with a globally burdensome disease. Psychological distress associated with a poor HRQoL should be considered in the making of decisions about the treatment of these patients.
TRIAL REGISTRATION
ClinicalTrials.gov, NCT02069002.
目的
与室内空气相关的非特异性健康投诉在工作环境中很常见。在某些人中，症状持续存在而没有充分的解释。本研究旨在探讨与持续性、非特异性室内空气相关症状的员工健康相关生活质量（HRQoL）相关的因素。
方法
我们展示了一项针对与室内空气相关的非特异性症状员工 HRQoL 的干预措施的随机对照试验的基线结果。主要的参与者纳入标准是存在持续性的、与室内空气相关的多器官症状，且没有已知的病理生理学或环境相关的解释。作为参与者 HRQoL 的比较（n=52），我们使用了来自 2011 年健康调查（BRIF8901）的一般人群数据，其中包括与参与者的工作状态和年龄相匹配的受试者的信息，以及患有哮喘、焦虑或抑郁障碍或其他具有工作残疾的慢性疾病的受试者的信息。
结果
与一般人群（M=0.95，SE=0.001，p<.001，Hedges'g=2.33）和哮喘患者（M=0.93，SE=0.005，p<.001，Hedges'g=1.46）、焦虑和抑郁障碍患者（M=0.89，SE=0.006，p<.001，Hedges'g=0.73）或具有工作残疾的慢性疾病患者（M=0.91，SE=0.003，p<.001，Hedges'g=1.11）相比，参与者表现出更大的、具有临床意义的 HRQoL 受损[M=0.83，SE=0.013]。抑郁、焦虑和失眠的常见症状以及工作恢复不良与较差的 HRQoL 相关。
结论
与室内空气相关的非特异性症状患者的 HRQoL 比一般人群中具有全球负担的疾病患者更差。与较差的 HRQoL 相关的心理困扰应在决定这些患者的治疗时予以考虑。
试验注册
ClinicalTrials.gov，NCT02069002。
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