室内空气症状所致功能障碍严重程度的连续体：患病率和决定因素。
The Continuum of Severity of Functional Impairment Due to Indoor Air Symptoms: Prevalence and Determinants.
机构信息
From the Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland (E.E., S.S., J.P.); Finnish Institute of Occupational Health, Helsinki, Finland (S.S.); and Department of Health Security, Environmental Health Unit, Finnish Institute for Health and Welfare, Kuopio, Finland (J.L., A.S., J.P.).
出版信息
J Occup Environ Med. 2023 Sep 1;65(9):717-724. doi: 10.1097/JOM.0000000000002884. Epub 2023 May 23.
OBJECTIVE
The aim of the study is to study functional impairment due to indoor air-related symptoms and associated characteristics.
METHODS
A questionnaire survey of a random sample of Finnish people aged 25 to 64 years. Analyses were done using multivariate multinomial logistic regression.
RESULTS
A total of 23.1% reported indoor air-related symptoms, 1.8% severe functional impairment due to symptoms, 5.3% moderate, 11.1% mild, and 4.9% reported no impairment. Those with severe functional impairment showed the strongest associations with comorbid diseases, for example, asthma and irritable bowel syndrome, perceived sensitivities to several environmental factors, like chemicals, and likelihood of having symptoms in multiple organs, while those with no or little functional impairment showed weak or even inverse associations. Similar results emerged with severity of indoor air-related symptoms.
CONCLUSIONS
Individuals with indoor air-related symptoms are a very heterogeneous group. This should be better considered in future research and clinical practice.
目的
本研究旨在研究与室内空气相关的症状所导致的功能障碍及其相关特征。
方法
对 25 至 64 岁的芬兰随机人群进行问卷调查。采用多元多项逻辑回归进行分析。
结果
共有 23.1%的人报告有与室内空气相关的症状，1.8%的人因症状导致严重的功能障碍，5.3%的人中度，11.1%的人轻度，4.9%的人无功能障碍。严重功能障碍的人表现出与共病的最强关联，例如哮喘和肠易激综合征，对多种环境因素（如化学物质）的敏感性，以及多个器官出现症状的可能性，而无或几乎无功能障碍的人表现出较弱甚至相反的关联。与室内空气相关症状的严重程度类似，也出现了类似的结果。
结论
与室内空气相关的症状患者是一个非常异质的群体。这在未来的研究和临床实践中应得到更好的考虑。
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