Sha J, Fedtke C, Tilia D, Yeotikar N, Jong M, Diec J, Thomas V, Bakaraju R C
Brien Holden Vision Institute, Sydney, NSW, Australia,
School of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia,
Clin Optom (Auckl). 2019 Mar 19;11:27-38. doi: 10.2147/OPTO.S190120. eCollection 2019.
To ascertain the impact of altering cylinder (cyl) power and axis on vision in astigmatism.
In a prospective, randomized, participant-masked, crossover clinical trial, 28 astigmatic participants were tested for the following conditions on different days: full sphero-cyl correction and undercorrection by 0.25, 0.50, and 0.75 DC while maintaining spherical equivalence. Axis was also misaligned between -30° and +30°, in 10° steps. For each configuration, monocular high- and low-contrast visual acuities (HCVA, LCVA) were measured at 6 m, and participants rated vision clarity (1-10), vision satisfaction (1-10), and vision acceptability (yes/no). Linear mixed models were used to compare visual performance in the overall group and in low, medium, and high cyl subgroups.
Undercorrecting cyl power affected all groups equally (≥0.073). Undercorrection by 0.75 DC was significantly different to full cyl power for all variables (≤0.007), while 0.25 DC undercorrection did not cause any significant decreases (>0.05). Undercorrection by 0.50 DC was significantly different to full cyl power for HCVA (=0.006, however not clinically significant) and vision acceptability (=0.034). Axis misalignment affected the cyl groups differently (0.001), with the greatest impact in the high cyl group, followed by the medium then the low-cyl group. Misalignment by ±30° caused significant decreases in almost all cases (≤0.003), while misalignments by ±10° or ±20° caused significant decreases for some cyl groups and test variables.
Undercorrection of cyl by ≤0.50 DC while maintaining spherical equivalence has no significant effect on HCVA, LCVA, vision clarity, and vision satisfaction, while the amount of axis misalignment that can be tolerated is dependent on the cyl power. These results may have practical ophthalmic applications, such as reducing the total number of stock keeping units of toric contact lenses.
确定改变柱镜(cyl)度数和轴位对散光患者视力的影响。
在一项前瞻性、随机、受试者遮蔽、交叉临床试验中,28名散光受试者在不同日期接受以下情况的测试:全球面柱镜矫正以及在保持球镜等效度的情况下欠矫0.25、0.50和0.75 DC。轴位也在-30°至+30°之间以10°步长进行错位调整。对于每种配置,在6米处测量单眼高对比度和低对比度视力(HCVA、LCVA),并让受试者对视力清晰度(1 - 10分)、视力满意度(1 - 10分)和视力可接受性(是/否)进行评分。使用线性混合模型比较整个组以及低、中、高柱镜亚组的视觉表现。
柱镜度数欠矫对所有组的影响相同(≥0.073)。0.75 DC欠矫与全柱镜度数在所有变量上均有显著差异(≤0.007),而0.25 DC欠矫未导致任何显著下降(>0.05)。0.50 DC欠矫与全柱镜度数在高对比度视力(=0.006,然而无临床意义)和视力可接受性(=0.034)方面有显著差异。轴位错位对柱镜组的影响不同(0.001),对高柱镜组影响最大,其次是中柱镜组,然后是低柱镜组。±30°的错位在几乎所有情况下均导致显著下降(≤0.003),而±10°或±20°的错位对某些柱镜组和测试变量导致显著下降。
在保持球镜等效度的情况下,柱镜欠矫≤0.50 DC对高对比度视力、低对比度视力、视力清晰度和视力满意度无显著影响,而可耐受的轴位错位量取决于柱镜度数。这些结果可能在眼科实际应用中具有价值,例如减少复曲面隐形眼镜的库存单位总数。