Leube Alexander, Kovats Imre, Wahl Siegfried, Sickenberger Wolfgang
Institute for Ophthalmic Research, Eberhard Karls University Tuebingen, Elfriede-Aulhorn-Str. 7, 72076 Tuebingen, Germany; Department of Optometry and Vision Science, Ernst Abbe University of Applied Science Jena, Carl-Zeiss-Promenade 2, 07745 Jena, Germany.
Kovats zum scharfen Aug AG, Rathausgasse 16, 5402 Baden, Switzerland.
Cont Lens Anterior Eye. 2017 Dec;40(6):394-400. doi: 10.1016/j.clae.2017.09.002. Epub 2017 Sep 19.
Pilot study to investigate the feasibility of an axis-free correction approach of regular astigmatism using soft, bifocal contact lenses (CL).
The investigation covers an optical simulation and a pilot study for the assessment of visual performance (over refraction OR, monocular visual acuity VA). The power of the two zones was adjusted according to the power of the astigmatic meridians, individually. Subjective performance was assessed in 30 participants with a mean horizontal cylindrical component of J=- 0.65±1.29 D (cylinder from -0.75 to -4.00 DC). OR and VA were measured directly after fitting the CL, after one hour and after 5days (3FUP).
Evaluating the modulation transfer function, CL increased the Strehl ratio by 10% and the transferred spatial frequency was improved from 6.6 cpd to 21.3 cpd. Analysis of Sturm's interval revealed a residual astigmatism of D=0.73 D. OR revealed a statistically significant reduction of spherical error between baseline and all follow up (ΔM=-2.14 D, p<0.001) and between the J from baseline to 3FUP (ΔJ=-0.46 D, p=0.04). Wearing the CL for 5days did not result in a significant difference of VA (ΔVA=+0.01 logMAR, p=0.99).
Axis-free correction of astigmatism using bifocal CL resulted in reasonable performance based on computer simulation. Participants showed no clinically reduced visual acuity or contrast sensitivity. Further clinical studies are needed to show if this approach provides a good alternative to conventional astigmatic correction.
进行一项初步研究,以探讨使用软性双焦点隐形眼镜(CL)对规则散光进行无轴位矫正方法的可行性。
该研究包括一项光学模拟和一项用于评估视觉性能(复验验光[OR]、单眼视力[VA])的初步研究。根据散光子午线的度数分别调整两个区域的屈光度。对30名参与者进行主观性能评估,其平均水平柱镜成分J = -0.65±1.29 D(柱镜度数从-0.75至-4.00 DC)。在佩戴CL后、1小时后和5天后(3次随访)直接测量OR和VA。
通过评估调制传递函数,CL使斯特列尔比提高了10%,传递的空间频率从6.6周/度提高到21.3周/度。对斯图姆间隔的分析显示残余散光为D = 0.73 D。OR显示基线与所有随访之间(ΔM = -2.14 D,p < 0.001)以及基线至3次随访时的J值之间(ΔJ = -0.46 D,p = 0.04)的球镜误差有统计学意义的降低。佩戴CL 5天并未导致VA有显著差异(ΔVA = +0.01 logMAR,p = 0.99)。
基于计算机模拟,使用双焦点CL对散光进行无轴位矫正取得了合理的效果。参与者未出现临床上视力下降或对比敏感度降低的情况。需要进一步的临床研究来证明该方法是否能成为传统散光矫正的良好替代方案。