Lukic Darko, Karabeg Reuf, Jahic Vildana, Stanojevic Andrea, Pavlovska Biljana, Krickovic Zoran, Predojevic Goran, Ivic Dusko, Gajic Ivana
Faculty of Medicine, University of Banja Luka, Banja Luka, Bosna and Herzegovina.
Health center «Karabeg» Sarajevo, Sarajevo, Bosnia and Herzegovina.
Mater Sociomed. 2018 Dec;30(4):251-254. doi: 10.5455/msm.2018.30.251-254.
The aim of this article is to determine the possible correlation between the smoking habit and the incidence of basocellular skin cancer (BCC).
The prospective study, which lasted from June 2012 to June 2018, included subjects diagnosed with basocellular skin cancer (BCC). Respondents were divided into 3 groups. The first, group A (21 respondents), are respondents who smoke 20-35 cigarettes a day. The second, group B (19 respondents), consists of respondents who smoke 35-50 cigarettes a day. The third, group C (91 respondents), consist of non-smokers. Observed parameters are sex, age, current and previous smoking habits, including duration (total smoking year) and intensity (average number of cigarettes smoked per day), age at the start of smoking, and prolonged exposure to the sun.
No statistically significant relationship was found between smoking and BCC frequency. It was shown that with BCC of the skin was more affected those who did not smoke. There is no clear relationship between the duration of smoking and/or the amount of smoking and the development of BCC, and it follows that this relationship is not likely to be causative. A suggestive, but not significant, evidence of relationship between smoking and skin cancer is found at this time.
Since it is a conglomerate of possible etiological factors, further research is needed to definitively clarify the effect of tobacco consumption on the development of BCC by monitoring a larger number of respondents over a longer period of time in large prospective studies. In any case, a possible association with skin cancer is a reason to avoid smoking.
本文旨在确定吸烟习惯与基底细胞皮肤癌（BCC）发病率之间的可能关联。
这项前瞻性研究从2012年6月持续至2018年6月，纳入了被诊断为基底细胞皮肤癌（BCC）的受试者。受访者被分为3组。第一组，A组（21名受访者），是每天吸烟20 - 35支的受访者。第二组，B组（19名受访者），由每天吸烟35 - 50支的受访者组成。第三组，C组（91名受访者），由不吸烟者组成。观察参数包括性别、年龄、当前和既往吸烟习惯，包括持续时间（总吸烟年数）和强度（每天平均吸烟支数）、开始吸烟的年龄以及长期日晒情况。
未发现吸烟与BCC发病率之间存在统计学显著关系。结果表明，皮肤基底细胞癌在不吸烟者中更为常见。吸烟持续时间和/或吸烟量与基底细胞癌的发生之间没有明确关系，因此这种关系不太可能是因果关系。此时发现了吸烟与皮肤癌之间有提示性但不显著的关联证据。
由于这是多种可能病因因素的综合，需要进一步研究，通过在大型前瞻性研究中对更多受访者进行更长时间的监测，以明确阐明烟草消费对基底细胞癌发生的影响。无论如何，与皮肤癌的可能关联是避免吸烟的一个理由。
