Sağmak Tartar Ayşe, Balın Şafak Özer, Akbulut Ayhan, Demirdağ Kutbeddin
Fırat Üniversitesi, Tıp Fakültesi Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji, Elazığ, Türkiye
Turkiye Parazitol Derg. 2019 Mar 28;43(1):26-29. doi: 10.4274/tpd.galenos.2019.6142.
The present study aimed to evaluate Crimean-Congo Haemorrhagic Fever (CCHF) in patients hospitalized in our hospital.
A total of 61 adult patients who were diagnosed as having CCHF between January 2011 and August 2018, in whom the diagnosis was confirmed by detecting virus-specific IgM by ELISA and/or by showing viral RNA by RT-PCR and who were managed at our clinic were evaluated retrospectively for their epidemiological and clinical findings, treatment and prognosis.
Of the 61 cases, 41 (67.2%) were male and 20 (32.8%) female. The mean age of the patients was 45.31±2.12 years. Sixty (98.4%) patients were living in rural area. Forty four patients (72.1 %) had a tick-bite history. According to months, most of the cases were seen in June, July and May, respectively. Fever, weakness and loss of appetite were the most common complaints of the patients. Treatment of ribavirin was started on the day of admission in all patients. One patient who was admitted in the late period died. The other 60 patients were discharged after being healed.
Especially during summers when the disease is seen frequently, the history of tick contact should be questioned and tick should be searched in the examination in the patients with suspected clinical findings. A significant number of the patients do not have a known tick contact. Therefore, training meetings should be organized about the symptoms and findings of the disease in the endemic areas and awareness should be raised among the community and the doctors working in emergency services and primary care.
本研究旨在评估我院收治的克里米亚-刚果出血热（CCHF）患者情况。
回顾性分析2011年1月至2018年8月间在我院确诊为CCHF的61例成年患者，这些患者通过酶联免疫吸附测定（ELISA）检测病毒特异性IgM和/或逆转录聚合酶链反应（RT-PCR）检测病毒RNA确诊，并在我院接受治疗，分析其流行病学、临床特征、治疗及预后情况。
61例患者中，男性41例（67.2%），女性20例（32.8%）。患者平均年龄为45.31±2.12岁。60例（98.4%）患者居住在农村地区。44例（72.1%）患者有蜱叮咬史。按月份统计，大多数病例分别出现在6月、7月和5月。发热、乏力和食欲不振是患者最常见的主诉。所有患者均在入院当天开始使用利巴韦林治疗。1例晚期入院患者死亡。其他60例患者治愈后出院。
特别是在疾病高发的夏季，对于疑似临床表现的患者，应询问蜱接触史并在检查时查找蜱。相当一部分患者并无已知的蜱接触史。因此，应在流行地区组织关于该疾病症状和表现的培训会议，提高社区以及从事急诊服务和初级保健工作的医生的认识。
