Feng Yutian, Louyakis Artemis S, Makkay Andrea M, Guerrero Ray O, Papke R Thane, Gogarten J Peter
Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA
Microbiol Resour Announc. 2019 Mar 21;8(12):e00096-19. doi: 10.1128/MRA.00096-19.
Isolated from Aran-Bidgol Lake in Iran, and reported here, strain Fb21 represents the first complete genome from this archaeal species. Local recombination in this genome is in stark contrast to equidistant recombination events in bacteria. The genome's GC bias, however, points to a genome architecture and origin that resemble those of a bacterium. Its availability, genome signatures, and frequent intragenomic recombination mean that Fb21 presents an attractive model organism for this species.
从伊朗的阿兰-比德戈尔湖分离出来并在此报告的菌株Fb21代表了该古细菌物种的首个完整基因组。该基因组中的局部重组与细菌中均匀分布的重组事件形成鲜明对比。然而,该基因组的GC偏倚表明其基因组结构和起源与细菌的相似。其可得性、基因组特征以及频繁的基因组内重组意味着Fb21为该物种提供了一个有吸引力的模式生物。